Our Anti-Cytokeratins 1-6, 8, 10, 13-16, 18, 19 mouse monoclonal primary antibody from Antibodies Incorporated is produced in-house from hybridoma clone Multiple clones. It detects human Cytokeratins 1-6, 8, 10, 13-16, 18, 19, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Cytokeratins are intermediate filament keratins found in the intracytoplasmic cytoskeleton of epithelial tissue. There are two types of Cytokeratins: the low weight, acidic type I cytokeratins and the high weight, basic or neutral type II. Cytokeratins are usually found in pairs comprising a type I Cytokeratin and a type II cytokeratin. The high molecular weight cytokeratins, which are the basic or neutral cytokeratins, comprise subtypes CK1 (67), CK2(65.5), CK3(64), CK4(59), CK5(58), CK6(56), CK7(54), CK8(52.5) and CK9. The low molecular weight cytokeratins, which are the acidic cytokeratins, comprise subtypes CK10 (56.5), CK12 (56), CK13 (53), CK14 (50), CK16 (48), CK17 (46), CK18 (45), CK19 (48) and CK20 (46). This antibody recognizes cytokeratins CK1 (67), CK2 (65.5), CK3 (64), CK4 (59) CK5 (58), CK6 (56), CK8 (52.5), CK10 (56.5), CK13 (54) CK14 (50), CK15 (50), CK16 (48), CK18 (45), CK 19 (40)
Purified by Protein A Chromatography
0.5 mg/mL
Monoclonal
Multiple clones
IgG1
ICC, IHC
Mouse
KRT1-6, 8, 10, 13-16, 18, 19
40-67 kDa
Human epidermal keratin
Human
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL594 Ex: 594 nm, Em: 615 nm
No cross-reactivity reported
Each new lot of this antibody is tested to confirm that it recognizes a single immunoreactive band of expected molecular weight when used in Western blot.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
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