Anti-Cavbeta2 Ca2+ Channel Antibody FL650 Conjugate (N8B/1)

Name: Anti-Cavbeta2 Ca2+ Channel Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-065-FL650
Price: 460.0 USD
Availability: InStock

Our Anti-Cavbeta2 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N8B/1. It detects human, mouse, and rat Cavbeta2 Ca2+ channel, and is purified by Protein A chromatography. It is great for use in CM, IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

490

550

594

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Data Sheet

SKU: 75-065-FL650

Product Details

Target

Cavbeta2 Ca2+ channel

Target Description

Voltage-dependent L-type calcium channel subunit beta-2 or Cav ß2 is encoded by the gene CACNB2. Cavß2 is a cytoplasmic subunit of L type voltage-sensitive calcium channels.These channels facilitate entry of calcium ions into excitable cells are involved in a variety of calcium dependent processes, including neurotransmitter release, muscle contraction, and gene expression. Cav ß2 is expressed heart and brain, and lung. Mutations in this gene are associated with Brugada syndrome.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N8B/1

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Cacnb2 Cacnlb2

Molecular Weight

78 kDa

Antigen

Synthetic peptide amino acids 189-205 of rat Cav2 (RSPKPSANSVTSPHSKE; accession number A0A0G2JSZ0)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939275

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with Cavβ1, Cavβ3, Cavβ4

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2)

UniProt Details

UniProt (Human): Q08289
UniProt (Immunogen Species): A0A0G2JSZ0

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Anti-Cavbeta2 Ca2+ Channel Antibody FL650 Conjugate (N8B/1)

SKU: 75-065-FL650

Product Details

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