Andreeva, L;David, L;Rawson, S;Shen, C;Pasricha, T;Pelegrin, P;Wu, H. NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. Cell. 2021 December 22; doi: 10.1016/j.cell.2021.11.011. Article
Hoechst 33342 Fluorescent Nucleic Acid Stain
Klein, M;Kaleem, A;Oetjen, S;Wünkhaus, D;Binkle, L;Schilling, S;Gjorgjieva, M;Scholz, R;Gruber-Schoffnegger, D;Storch, S;Kins, S;Drewes, G;Hoffmeister-Ullerich, S;Kuhl, D;Hermey, G. Converging roles of PSENEN/PEN2 and CLN3 in the autophagy-lysosome system. Autophagy. 2021 December 29; doi: 10.1080/15548627.2021.2016232. Abstract
Magic Red Cathepsin B Assay
Yadav, VK;Berger, JM;Singh, P;Nagarajan, P;Karsenty, G. Embryonic osteocalcin signalling determines lifelong adrenal steroidogenesis and homeostasis in the mouse. The Journal of clinical investigation. 2021 December 14; doi: 10.1172/JCI153752. Full Text
Antibody Coating Buffer
Chassefeyre, R;Chaiamarit, T;Verhelle, A;Novak, SW;Andrade, LR;Leitão, ADG;Manor, U;Encalada, SE. Endosomal sorting drives the formation of axonal prion protein endoggresomes. Science advances. 2021 December 24; doi: 10.1126/sciadv.abg3693. Full Article
Magic Red Cathepsin B Assay
Panigrahi, S;Goswami, T;Ferrari, B;Antonelli, CJ;Bazdar, DA;Gilmore, H;Freeman, ML;Lederman, MM;Sieg, SF. SARS-CoV-2 Spike Protein Destabilizes Microvascular Homeostasis. Microbiology spectrum. 2021 December 22; doi: 10.1128/Spectrum.00735-21. Full Text
SR FLICA Poly Caspase Assay
Liu, Y;Zhang, Y;Feng, Q;Liu, Q;Xie, J;Li, H;Yang, F;Liu, X;Gao, W;Bai, X;Li, Z;Wang, Y. GPA Peptide Attenuates Sepsis-Induced Acute Lung Injury in Mice via Inhibiting Oxidative Stress and Pyroptosis of Alveolar Macrophage. Oxidative medicine and cellular longevity. 2021 December 28; doi: 10.1155/2021/5589472. Article
FAM FLICA Caspase-1 (YVAD) Assay
Khodayari, N;Wang, RL;Oshins, R;Lu, Y;Millett, M;Aranyos, AM;Mostofizadeh, S;Scindia, Y;Flagg, TO;Brantly, M. The Mechanism of Mitochondrial Injury in Alpha-1 Antitrypsin Deficiency Mediated Liver Disease. International journal of molecular sciences. 2021 December 9; doi: 10.3390/ijms222413255. Abstract
MitoPT TMRM Assay
Castelli, R;Ibarra, M;Faccio, R;Miraballes, I;Fernández, M;Moglioni, A;Cabral, P;Cerecetto, H;Glisoni, R;Calzada, V. T908 Polymeric Micelles Improved the Uptake of Sgc8-c Aptamer Probe in Tumor-Bearing Mice: A Co-Association Study between the Probe and Preformed Nanostructures. Pharmaceuticals. 2021 December 23; doi: 10.3390/ph15010015. Article
Hoechst 33342 Fluorescent Nucleic Acid Stain
Hatoyama, Y;Homma, Y;Hiragi, S;Fukuda, M. Establishment and analysis of conditional Rab1- and Rab5-knockout cells using the auxin-inducible degron system. Journal of cell science. 2021 December 15; doi: 10.1242/jcs.259184. Article
Magic Red Cathepsin B Assay
Samukawa, S;Yoshimi, R;Kirino, Y;Nakajima, H. The PRY/SPRY domain of pyrin/TRIM20 interacts with ?2-microglobulin to promote inflammasome formation. Scientific reports. 2021 December 8; doi: 10.1038/s41598-021-03073-6. Text
Pyroptosis/Caspase-1 Assay, Green
Fante, T;Simino, LAP;Fontana, MF;Reginato, A;Ramalheira, TG;Rodrigues, HG;Lisboa, PC;de Moura, EG;Ignácio-Souza, LM;Milanski, M;Torsoni, MA;Torsoni, AS. Maternal high-fat diet consumption programs male offspring to mitigate complications in liver regeneration. Journal of developmental origins of health and disease. 2021 December 3; doi: 10.1017/S2040174421000659. Full Abstract
Propidium Iodide Stain
Onizawa, Y;Katoh, T;Miura, R;Konda, K;Noguchi, T;Iwata, H;Kuwayama, T;Hamano, S;Shirasuna, K. Acetoacetate is a trigger of NLRP3 inflammasome activation in bovine peripheral blood mononuclear cells. Veterinary immunology and immunopathology. 2021 December 17; doi: 10.1016/j.vetimm.2021.110370. Full Text
FAM FLICA Caspase-1 (YVAD) Assay