High Quality Antibodies for Array Tomography Imaging

Antibodies Inc and Aves Labs antibodies power array tomography for high-dimension analysis of complex biological structures!

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What is Array Tomography?

Array Tomography (AT) is a powerful technique that enables quantitive, high-resolution, large-field volumetric imaging of large numbers of antigens, fluorescent proteins, and ultrastructure in individual tissues.

This technique can reveal important and previously unseen features of brain molecular architecture.

AT involves preparing ultrathin serial sections from brain tissue that has been embedded in acrylic resin and subjecting this array of sections to multiplex immunofluorescence antibody (Ab) labeling and imaging.

Array tomography is a powerful volume microscopy technique for high dimensional analysis of complex protein population in tissues, organelles, synapses and cells.

ANTIGEN HOST ANTIBODY SOURCE
Synaptic
PSD95 Mouse NeuroMab 75-348
Homer1 Mouse NeuroMab 75-454
Gephyrin Mouse NeuroMab 75-465
Cell type markers
Calbindin Mouse NeuroMab 75-448
Receptors 
GluN2B 
Mouse NeuroMab 75-101
Cytoskeletal 
Neurofilament, heavy chain 
Chicken AVES NFH
Neurofilament, light chain** Chicken AVES NFL
Glial 
GFAP 
Chicken AVES GFAP
Myelin 
PLP 
Chicken AVES PLP
CNPase Chicken AVES CNP
Ion Channels 
Kv1.1** 
Mouse NeuroMab 75-105
Kv1.2** Mouse NeuroMab 75-008
Kv2.1** Mouse NeuroMab 75-014
Other 
Caspr** 
Mouse NeuroMab 75-001

Figure 1. NeuroMab and Aves Labs antibodies commonly used for array tomography.

Neuroscientists, maximize your results with every precious sample!

Our innovative combination of dyes and antibodies allows you to study multiple proteins simultaneously. With our solutions, you can perform multiplexing assays like flow cytometry, immunofluorecence, and immunohistochemistry, saving you time and boosting your research efficiency. Unlock more with every experiment!

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Reference: Micheva KD, Gong B, Collman F, Weinberg RJ, Smith SJ, Trimmer JS, Murray KD. Developing a Toolbox of Antibodies Validated for Array Tomography-Based Imaging of Brain Synapses. bioRxiv [Preprint]. 2023 Nov 8:2023.06.28.546920.

Antibody techniques