Anti-GABA-A-R-Alpha2 Antibody (BSA and Azide free) (N399/19)

Our carrier-free Anti-GABA-A-R-Alpha2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N399/19. It is KO validated, detects mouse and rat GABA-A-R-Alpha2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Mouse, Rat
ELISA, ICC, IHC, WB
Mouse
Unconjugated
490
550
594
650

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Data Sheet
KO Validated KO Validated

SKU: 75-384-CF

Volume: 100 µL
1-5 business days
Price:
$475.00

Product Details

GABA-A-R-Alpha2
Gamma-aminobutyric acid receptor subunit alpha-2 or GABA AR-Alpha2 is encoded by the gene GABRA2. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR alpha 5 is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR-Alpha2 is primarily expressed in brain at the cell junction, synapse,and the postsynaptic cell membrane. Diseases associated with GABRA2 include Alcohol Dependence and Alcohol Use Disorder.
Purified by Protein A chromatography
1 mg/mL
Monoclonal
N399/19
IgG1
ELISA, ICC, IHC, WB
Mouse
Gabra2 Gabra-2
55 kDa
Fusion protein amino acids 350-385 (cytoplasmic C-terminus) of rat GABA-A-R-Alpha2 (accession number P23576) produced recombinantly in E. Coli
Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.
PBS
Unconjugated
Does not cross-react with GABA-A-R-Alpha1
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
Gamma-aminobutyric acid receptor subunit alpha-2 (GABA(A) receptor subunit alpha-2)
P23576

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