Anti-ANO6/TMEM16F Antibody FL490 Conjugate (N429/19)

Name: Anti-ANO6/TMEM16F Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-418-FL490
Price: 474.0 USD
Availability: InStock

Our Anti-ANO6/TMEM16F mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N429/19. It is KO validated, detects human, mouse, and rat ANO6/TMEM16F, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

KO Validated

SKU: 75-418-FL490

Volume: 200 µL

Variant

Price:

$474.00

Quantity:

Product Details

Target

ANO6/TMEM16F

Target Description

Anoctamin-6, Transmembrane Protein 16F or -ANO6/TMEM16F is encoded by the gene ANO6. ANO6 belongs to the anoctamin family of membrane proteins many of which are calcium-activated chloride channels. ANO6 plays a role as a regulator of phospholipid scrambling in platelets (which is involved in blood clotting). ANO6 is expressed in epithelial tissues. Diseases associated with ANO6 include Scott Syndrome and Miyoshi Muscular Dystrophy 3.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N429/19

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

ANO6 TMEM16F

Molecular Weight

110 kDa

Antigen

Fusion protein amino acids 1-294 (cytoplasmic N-terminus) of human ANO6 (accession number Q4KMQ2) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940388

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with ANO5/TMEM16E

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F)

UniProt Details

UniProt (Human): Q4KMQ2
UniProt (Immunogen Species): Q4KMQ2

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Anti-ANO6/TMEM16F Antibody FL490 Conjugate (N429/19)

SKU: 75-418-FL490

Product Details

Bulk Order Anti-ANO6/TMEM16F Antibody FL490 Conjugate

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