Fluorescent Sarcosine Detection Kit
This kit provides a reliable, sensitive fluorometric assay for quantifying sarcosine in biological samples. A non-fluorescent detection reagent, is reduced via an enzyme-coupled reaction in the presence of sarcosine to yield a fluorescent product.
Sarcosine is natural amino acid that is an important intermediate in the metabolism of choline. Sarcosine is an important component of proteins and plays a significant role in metabolic processes of living cells as a source of serine, creatine, purines and glutathione etc. Sarcosine is present in such food sources like legumes, eggs, ham, turkey etc. It is used in a variety of industrial applications such as manufacturing of tooth paste and biodegradable surfactants. Sarcosine was recently reported to activate prostate cancer cells and is indicated as a possible marker for prostate cancer progression to metastasis. It is also used in adjunctive treatment for Schizophrenia and depression.
This kit provides a reliable, sensitive fluorometric assay for quantifying sarcosine in biological samples. A non-fluorescent detection reagent, is reduced via an enzyme-coupled reaction in the presence of sarcosine to yield a fluorescent product. The kit is suitable for use with serum, cells, and tissue extracts.
Product Specific References
| PMID | Publication |
| 30332646 | Walters, R. O., et al. 2018. Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans. Cell Rep, 663-676. |