Chicken polyclonals have grown in popularity especially when performing multiplex analysis using secondary antibodies. As most primary antibodies are raised in rabbit or mouse hosts, chicken provides an alternative species thus minimizing primary antibody cross reactivity of the fluorescently labelled secondary antibodies.Aves Labs is one of the few manufacturers to use chicken eggs due to the process being ethical and animal friendly. Furthermore, Aves Labs collects about 18 "immune eggs" from each hen, but only use 6 "immune eggs" to prepare a batch of IgY antibody. The remaining 12 "immune eggs" are stored in the refrigerator, as reserve stock.
Our centromere antibodies are purified IgG derived from human anti-centromere positive serum (CREST patient serum). They are useful as diagnostic markers in immunological assays such as IHC and ICC, as well as controls in ANA diagnostics, helping identify autoimmune reactions and offering insights into various autoimmune diseases.