Anti-FBXW7 (hCdc4) Antibody

Name: Anti-FBXW7 (hCdc4) Antibody
Brand: PhosphoSolutions
SKU: 24253
Price: 430.0 USD
Availability: InStock

Our FBXW7 rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human FBXW7 and is antigen affinity purified. It is great for use in WB.

Species Reactivity

Human

Applications

Host Species

Rabbit

Go to Full Product Details

SKU: 24253

Title: 100 µL

Variant

Price:

$430.00

Quantity:

Product Details

Target

FBXW7

Target Description

Cyclin E, one of the activators of the cyclin-dependent kinase Cdk2, is critical for the initiation of DNA replication and other S-phase functions. The proper timing and amplitude of cyclin E expression seem to be important, because elevated levels of cyclin E have been associated with a variety of malignancies and constitutive expression of cyclin E leads to genomic instability. Phosphorylated cyclin E depends on the novel human gene, hCdc4, that was found to be mutated in a cell line derived from breast cancer that expressed extremely high levels of cyclin E.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Gene Name

FBXW7

Antigen

Synthetic peptide corresponding to amino acids from the N-terminal region of human Cdc4 protein

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the N terminus of the 69 kDa isoform of the hCdc4 protein

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

Cdc4, FBXW7, Archipelago, AGO, F box and WD 40 domain protein 7, FBW7, SEL10

UniProt Details

UniProt (Human): Q969H0
UniProt (Immunogen Species): Q969H0

Recover password

Create my account

Anti-FBXW7 (hCdc4) Antibody

SKU: 24253

Product Details

Bulk Order Anti-FBXW7 (hCdc4) Antibody

Related Products

Recently Viewed