Anti-TrpC1 Antibody (1F1)
Our Anti-TrpC1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone 1F1. It is KO validated, detects human, mouse, and rat TrpC1, and is purified by Protein A chromatography. It is great for use in ICC, WB.
SKU: 75-278
Product Details
TrpC1
Short transient receptor potential channel 1 or TrpC1 is encoded by the gene TRPC1.TrpC1 belongs to the transient receptor family, a group of membrane bound ion channels that have a relatively non-selective permeability to cations, including sodium, calcium and magnesium. TrpC1 expression seems to be ubiquitous, and is widely expressed in throughout the brain.
Purified by Protein A chromatography
1 mg/mL
Monoclonal
1F1
IgG1
ICC, WB
Mouse
TRPC1 TRP1
80-90 kDa
Fusion protein amino acids 27-306 (cytoplasmic N-terminus) of human TRPC1 (accession number P48995) produced recombinantly in E. Coli.
Human, Mouse, Rat
AB_2315951
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Unconjugated
Does not cross-react with TRPC4 (based on KO validation results)
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Shipped on ice packs
Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (TRP-1)
UniProt (Human): P48995
UniProt (Immunogen Species): P48995
UniProt (Immunogen Species): P48995
- Ludlow MJ1, Gaunt HJ1, Rubaiy HN1, Musialowski KE1, Blythe NM1, Vasudev NS1, Muraki K2, Beech DJ3. (2017), '(-)-Englerin A-evoked Cytotoxicity Is Mediated by Na+ Influx and Counteracted by Na+/K+-ATPase..' J Biol Chem. 10.1074/jbc.M116.755678.
- Hong C1, Seo H2, Kwak M1, Jeon J2, Jang J2, Jeong EM3, Myeong J1, Hwang YJ4, Ha K1, Kang MJ5, Lee KP6, Yi EC5, Kim IG3, Jeon JH1, Ryu H7, So I8. (2015), 'Increased TRPC5 glutathionylation contributes to striatal neuron loss in Huntington's disease..' Brain. . 10.1093/brain/awv188.