Anti-AGPS Neo-Epitope Antibody (N444/63)

Name: Anti-AGPS Neo-Epitope Antibody
Brand: NeuroMab
SKU: 75-434
Price: 319.0 USD
Availability: InStock

Our Anti-AGPS neo-epitope mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N444/63. It detects human, mouse, and rat AGPS neo-epitope, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Adult rat brain membrane (RBM) and human cell immunoblot: lysates of RBM and fibroblasts from unaffected (control/normal) and disease-affected (patient/Pex5-mutant) humans probed with N444/63 TC supe (left) and rabbit polyclonal (right). Human fibroblast samples courtesy of Ning Huang and Joseph Hacia (USC) and rabbit polyclonal courtesy of Nancy Braverman (McGill).

Adult rat hippocampus immunohistochemistry.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-434

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

AGPS neo-epitope

Target Description

Alkyldihydroxyacetonephosphate synthase, peroxisomal or AGPS neo-epitope is encoded by the gene AGPS. AGPS is a member of the FAD-binding oxidoreductase/transferase type 4 family and is an enzyme involved in ether lipid biosynthesis. Diseases associated with this gene include forms of Rhizomelic Chondrodysplasia Punctata.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N444/63

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

AGPS AAG5

Molecular Weight

66 kDa processed (vs. 72 kDa unprocessed)

Antigen

Synthetic peptide amino acids 59-67 (KARRAASAA, site of proteolytic processing for peroxisome import) of human AGPS (accession number O00116)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2629423

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with unprocessed AGPS

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Alkyldihydroxyacetonephosphate synthase, peroxisomal (Alkyl-DHAP synthase) (EC 2.5.1.26) (Aging-associated gene 5 protein) (Alkylglycerone-phosphate synthase)

UniProt Details

UniProt (Human): O00116
UniProt (Immunogen Species): O00116

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Anti-AGPS Neo-Epitope Antibody (N444/63)

SKU: 75-434

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