Anti-Ankyrin-B Antibody FL490 Conjugate (N105/17)

Name: Anti-Ankyrin-B Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-145-FL490
Price: 531.0 USD
Availability: InStock

Our Anti-Ankyrin-B mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N105/17. It detects human, mouse, and rat Ankyrin-B, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Guinea Pig, Human, Mouse, Rat

Applications

ICC, IHC, IP

Host Species

Mouse

Conjugates and Formulations

Unconjugated

550

594

650

Carrier-Free

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Data Sheet

SKU: 75-145-FL490

Volume: 200 µL

Variant

Price:

$531.00

Quantity:

Ships: 1-5 business days

Product Details

Target

Ankyrin-B

Target Description

Ankyrin-2 or -Ankyrin-B is encoded by the gene ANK2. Ankyrin B is a scaffold protein that functions to link proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane cytoskeleton. In this manner, ankyrin family proteins play key roles in various processes including cell motility, activation, proliferation, contact and the maintenance of specialized membrane domains. Ankyrin B is expressed in brain and muscle. Mutations in this gene cause long QT syndrome 4 and cardiac arrhythmia syndrome.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N105/17

Isotype

IgG2a

Applications

ICC, IHC, IP

Host Species

Mouse

Gene Name

ANK2 ANKB

Molecular Weight

<200 kDa

Antigen

Fusion protein amino acids 203-496 of human Ankyrin-B (accession number Q01484) produced recombinantly in E. Coli

Species Reactivity

Guinea Pig, Human, Mouse, Rat

Antibody Registry ID

AB_2939536

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)

UniProt ID

Q01484

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Anti-Ankyrin-B Antibody FL490 Conjugate (N105/17)

SKU: 75-145-FL490

Product Details

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