Anti-ATF4 Antibody FL650 Conjugate (N360A/24)

Name: Anti-ATF4 Antibody FL650 Conjugate
Brand: NeuroMab
SKU: 75-345-FL650
Price: 460.0 USD
Availability: InStock

Our Anti-ATF4 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N360A/24. It detects human and rat ATF4, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

490

550

594

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Data Sheet

SKU: 75-345-FL650

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

ATF4

Target Description

Cyclic AMP-dependent transcription factor ATF-4, Cyclic AMP-Responsive Element-Binding Protein 2, CREB2 or ATF4 is encoded by the gene ATF4 and is a member of the basic leucine-zipper (bZIP) superfamily. ATF4 is a transcriptional activator believed to be involved in many cell processes. ATF4 is widely expressed in tissues. In brain, ATF4 has been shown to localize in hippocampal neuron dendritic membranes. Diseases associated with ATF4 include Deafness, Mehmo Syndrome and T-Cell Leukemia.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N360A/24

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

ATF4 CREB2 TXREB

Molecular Weight

60 kDa

Antigen

Fusion protein amino acids 25-327 (nearly full-length, all but first 24 amino acids) of human ATF4 (accession number P18848) produced recombinantly in E. Coli

Species Reactivity

Human, Rat

Antibody Registry ID

AB_2940175

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL650 Ex: 655 nm, Em: 676 nm

Specificity

Does not cross-react with ATF5

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (DNA-binding protein TAXREB67) (Tax-responsive enhancer element-binding protein 67) (TaxREB67)

UniProt Details

UniProt (Human): P18848
UniProt (Immunogen Species): P18848

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Anti-ATF4 Antibody FL650 Conjugate (N360A/24)

SKU: 75-345-FL650

Product Details

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