Anti-Beta-Defensin Antibody

Name: Anti-Beta-Defensin Antibody
Brand: PhosphoSolutions
SKU: 24216
Price: 430.0 USD
Availability: InStock

Our Beta-Defensin rabbit polyclonal primary antibody from PhosphoSolutions is produced in-house. It detects human Beta-Defensin and is antigen affinity purified. It is great for use in WB.

Species Reactivity

Human

Applications

Host Species

Rabbit

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SKU: 24216

Title: 100 µL

Variant

Price:

$430.00

Quantity:

Product Details

Target

Beta-Defensin

Target Description

A novel, nonhemolytic antimicrobial peptide (human beta-defensin-3, hBD-3) was isolated from human lesional psoriatic scales and cloned from keratinocytes. hBD-3 demonstrated a salt-insensitive broad spectrum of potent antimicrobial activity against many potentially pathogenic microbes including multiresistant S. aureus and vancomycin-resistant Enterococcus faecium. Keratinocytes and airway epithelial cells are cellular sources of hBD-3. Tumor necrosis factor alpha and contact with bacteria were found to induce hBD-3 mRNA expression. hBD-3 therefore might be important in the innate epithelial defense of infections by various microorganisms seen in skin and lung, such as cystic fibrosis.

Format

Antigen Affinity Purified

Clonality

Polyclonal

Isotype

IgG

Applications

Host Species

Rabbit

Gene Name

DEFB1

Antigen

Synthetic peptide corresponding to amino acids from the N-terminal region of human beta Defensin protein

Species Reactivity

Human

Storage

Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.

Physical State

Liquid

Buffer

PBS + 0.02% NaN3

Dilution Ranges

WB: 1:500-1:1000
WB Brain: 1:500-1:1000

Specificity

Reacts with the N-terminal region of human beta Defensin protein

Quality Control

Western blots performed on each lot.

Usage Statement

For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.

Country of Origin

United States

Expiration

After date of receipt, stable for at least 1 year at -20°C.

Shipping

Blue Ice

Synonyms

DEFB1, BD1, Defensin beta 1 preproprotein, HBD

UniProt Details

UniProt (Human): P60022
UniProt (Immunogen Species): P60022

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Anti-Beta-Defensin Antibody

SKU: 24216

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