Anti-Beta1-Spectrin Antibody FL490 Conjugate (N385/21)

Name: Anti-Beta1-Spectrin Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-374-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-Beta1-spectrin mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N385/21. It detects human, mouse, and rat Beta1-spectrin, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-374-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Beta1-spectrin

Target Description

Spectrin beta chain, erythrocytic, Beta1 spectrin, or Membrane Cytoskeletal Protein is encoded by the gene SPTB and is a member of the member of the spectrin gene family. Beta1 spectrin is primary member of the cytoskeletal network in the erythrocyte plasma membrane. Beta1 spectrin is involved in cell membrane organization and stability and associates with the proteins band 4.1 and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. Diseases associated with this gene include Spherocytosis and Elliptocytosis.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N385/21

Isotype

IgG2b

Applications

ICC, IHC

Host Species

Mouse

Gene Name

SPTB SPTB1

Molecular Weight

250 kDa

Antigen

Fusion protein amino acids 1555-2137 (C-terminal repeats 13 to 17) of human Beta1-spectrin (accession number P11277) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940248

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Spectrin beta chain, erythrocytic (Beta-I spectrin)

UniProt Details

UniProt (Human): Q01082
UniProt (Immunogen Species): P11277

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Anti-Beta1-Spectrin Antibody FL490 Conjugate (N385/21)

SKU: 75-374-FL490

Product Details

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