Anti-Clcn5 Antibody (BSA and Azide free) (N406/47)

Name: Anti-Clcn5 Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-400-CF
Price: 475.0 USD
Availability: InStock

Our carrier-free Anti-Clcn5 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N406/47. It detects human, mouse, and rat Clcn5, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, ICC, IHC

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

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Data Sheet

SKU: 75-400-CF

Volume: 100 µL

Variant

Price:

$475.00

Quantity:

Product Details

Target

Clcn5

Target Description

Chloride Voltage-Gated Channel 5, CLCN5 or H(+)/Cl(-) exchange transporter 5 is encoded by the gene CLCN5 and is a member of the voltage-gated chloride channel (ClC) family. CLCN5 is a proton-coupled chloride transporter. CLCN5 is involved in the acidification of the endosome lumen and is thought to play an important role in renal tubular function. CLCN5 is expressed in kidney, aortic and coronary vascular smooth muscle. Diseases associated with CLCN5 include Dent Disease 1 and X-Linked Recessive Hypophosphatemic Rickets.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N406/47

Isotype

IgG1

Applications

ELISA, ICC, IHC

Host Species

Mouse

Gene Name

Clcn5

Molecular Weight

90 kDa

Antigen

Fusion protein amino acids 568-746 (C-terminus) of rat Clcn5 (accession number P51796) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

Does not cross-react with Clcn4

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

H(+)/Cl(-) exchange transporter 5 (Chloride channel protein 5) (ClC-5) (Chloride transporter ClC-5)

UniProt ID

P51796

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Anti-Clcn5 Antibody (BSA and Azide free) (N406/47)

SKU: 75-400-CF

Product Details

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