Anti-Complement C5b-9 Antibody Biotin Conjugate (aE11)

Name: Anti-Complement C5b-9 Antibody Biotin Conjugate
Brand: Antibodies Incorporated
SKU: DIA 011-01B-015
Price: 1330.0 USD
Availability: InStock

Our mouse Complement C5b-9 monoclonal biotinylated antibody from Antibodies Incorporated is produced from clone aE11. It detects horse, human, non-human primate, and pig Complement C5b-9 and is Protein A or Protein G purified. Works in ELISA.

Anti-Complement C5b-9 Antibody Biotin Conjugate

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Species Reactivity

Horse, Human, Monkey

Applications

ELISA

Host Species

Mouse

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Data Sheet

SKU: DIA 011-01B-015

Volume: 150 uL

Variant

Price:

$1,330.00

Quantity:

Ships: 1-2 business days

Product Details

Target

Complement C5b-9

Scientific Background

C5b-9 is also known as the terminal complement complex (TCC). The TCC consists of C5b, C6, C7, C8 and C9 and forms the membrane attack complex (MAC) as well as the non-lytic fluid-phase SC5b-9 complex (with protein S). The MAC forms channels in target cell membranes leading to cell lysis by osmotic leakage. The complexes contain neoantigens that are absent from the individual native components from which they are formed and DIA 011-01 is directed against a neoepitope exposed on C9 when incorporated into the TCC.

Format

Protein A or Protein G purified

Concentration

1 mg/mL ±15%

Clonality

Monoclonal

Clone

aE11

Isotype

IgG2a/k

Applications

ELISA

Host Species

Mouse

Gene Name

C5, C6, C7, C8, C9

Immunogen

Purified C5b-9

Immunogen Species

Human

Species Reactivity

Horse, Human, Monkey

Storage

2-8°C without exposure to light

Physical State

Liquid

Production Notes

BSA free

Buffer

0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide

Application Details

DIA 011-01 can be used in ELISA.

Conjugate

Biotin

Specificity

DIA 011-01 binds both membrane-bound MAC (active) and fluid-phase SC5b-9 complexes (inactive). (1) DIA 011-01 binds to a neoepitope exposed on C9

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Synonyms

C5, C5D, C5a, C5b, CPAMD4, ECLZB, complement C5, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4, C5a anaphylatoxin, anaphylatoxin C5a analog, complement component 5, prepro-C5

UniProt ID

P01031, P13671, P06681, P07357, P07358, P07360, P02749

NCBI Gene ID

727

Shipping

Shipped on ice packs

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Anti-Complement C5b-9 Antibody Biotin Conjugate (aE11)

SKU: DIA 011-01B-015

Product Details

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