Anti-DsbA-L (Disulfide-bond-A Oxidoreductase-like Protein) Antibody

3 Citations

Our Anti-DsbA-L (Disulfide-bond-A oxidoreductase-like protein) primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human and mouse DsbA-L and is serum. It is great for use in WB, IHC.

Western blot of mouse adipose tissue lysate showing specific immunolabeling of the ~25 kDa DsbA-L protein.
Western blot of mouse adipose tissue lysate showing specific immunolabeling of the ~25 kDa DsbA-L protein.
Roll over image to zoom in Click on image to zoom
Western blot of mouse adipose tissue lysate showing specific immunolabeling of the ~25 kDa DsbA-L protein.

Human, Mouse
IHC, WB
Rabbit

Go to Full Product Details

Data Sheet
Trial Size Trial Size

SKU: 465-DsbA-L

Volume: 100 µL
Price:
$385.00
Ships: 1-2 business days

Product Details

DsbA-L
Disulfide-bond-A oxidoreductase-like protein (DsbA-L, previously named as GST Kappa) is an adiponectin-interacting protein. DsbA-L is highly expressed in adipose tissue, and its expression level is negatively correlated with obesity in mice and humans. DsbA-L expression in 3T3-L1 adipocytes is stimulated by the insulin sensitizer rosiglitazone and inhibited by the inflammatory cytokine TNFalpha. Polymorphism of DsbA-L gene has recently been implicated in insulin secretion and body fat distribution (Gao F et al., 2009). Overexpression of DsbA-L promotes adiponectin multimerization while suppressing DsbA-L expression by RNAi markedly and selectively reduces adiponectin levels and secretion in 3T3-L1 adipocytes. Recent studies identify DsbA-L as a key regulator for adiponectin biosynthesis (Liu et al., 2008).
Serum
Polyclonal
IgG
IHC, WB
Rabbit
GSTK1
25 kDa
Full length recombinant mouse DsbA-L protein.
Human, Mouse
AB_2492080
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Liquid
Serum
Serum in 40% glycerol
WB: 1:2000
IHC: 1:200
Unconjugated
Specific for endogenous levels of the ~25 kDa DsbA-L protein. It is suggested that you add 1% BSA to the antibody dilution buffer.
Western blots performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.
Blue Ice
DSBA like thioredoxin domain containing protein antibody, Glutathione S-transferase kappa 1, EC:2.5.1.18, GST 13-13, GST class-kappa, GST kappa, GSTK1-1, mGSTK1, Glutathione S-transferase subunit 13
Q9DCM2

Product Specific References for Applications and Species

Western Blot: Mouse
PMID Dilution Publication
25900100 not listed DeClerca, V., et al. 2015. Fatty acids increase adiponectin secretion through both classical and exosome pathways. Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, 1851(9), pp.1123-1133.
20980258 not listed Wang, A., et al. 2011. Up-regulation of adiponectin by resveratrol the essential roles of the akt/foxo1 and amp-activated protein kinase signaling pathways and dsba-l. Journal of Biological Chemistry, 286(1), pp.60-66.
19011089 not listed Liu, M., et al. 2008. A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization. Proceedings of the National Academy of Sciences, 105(47), pp.18302-18307.

Bulk Order Anti-DsbA-L (Disulfide-bond-A Oxidoreductase-like Protein) Antibody

Product Specific Protocols

Related Products

Recently Viewed