Anti-GABA-A-R, Alpha1 Antibody (BSA and Azide free) (N95/35)

Name: Anti-GABA-A-R, Alpha1 Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-136-CF
Price: 475.0 USD
Availability: InStock

Our carrier-free Anti-GABA(A)R, Alpha1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N95/35. It is KO validated, detects human and mouse GABA(A)R, Alpha1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Species Reactivity

Frog, Human, Mouse, Rat, Xenopus

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

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Data Sheet

KO Validated

SKU: 75-136-CF

Volume: 100 µL

Variant

Price:

$475.00

Quantity:

Product Details

Target

GABA(A)R, Alpha1

Target Description

GABA(A)R, Alpha1 (Gamma-aminobutyric acid receptor subunit alpha-1) makes up two of the five subunits in the membrane bound GABA A receptor, the others being two β2 subunits and a single γ2 subunit. The receptor is a ligand gated chloride ion channel found postsynaptically and binds GABA, the major inhibitory neurotransmitter in the CNS. Mutations in GABA(A)R, Alpha1 have been linked to several types of epilepsy.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N95/35

Isotype

IgG2a

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

GABRA1

Molecular Weight

55 kDa

Antigen

Fusion protein amino acids 355-394 of mouse GABA-AR-Alpha1 (accession number P62812) produced recombinantly in E. Coli

Species Reactivity

Frog, Human, Mouse, Rat, Xenopus

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

No cross-reactivity against GABA-A-R-Alpha2 or -Alpha3

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Gamma-aminobutyric acid receptor subunit alpha-1 (GABA(A) receptor subunit alpha-1)

UniProt ID

P14867

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Anti-GABA-A-R, Alpha1 Antibody (BSA and Azide free) (N95/35)

SKU: 75-136-CF

Product Details

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