Anti-GABA-A-R-Alpha6 Antibody FL490 Conjugate (N229A/32)

Name: Anti-GABA-A-R-Alpha6 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-388-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-GABA-A-R-Alpha6 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N229A/32. It detects mouse and rat GABA-A-R-Alpha6, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-388-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

GABA-A-R-Alpha6

Target Description

Gamma-aminobutyric acid receptor subunit alpha-6 or GABA-A-R-Alpha6 is encoded by the gene GABRA6. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR alpha 5 is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR-Alpha6 is primarily expressed in brain at the cell junction, synapse, the postsynaptic cell membrane and cytoplasmic vesicle membrane. Diseases associated with GABRA6 include neurotic disorder and several forms of epilepsy.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N229A/32

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Gabra6 Gabra-6

Molecular Weight

50 kDa

Antigen

Fusion protein amino acids 325-420 (last cytoplasmic domain before extracellular C-terminus) of mouse GABA-A-R-Alpha6 (accession number P16305) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940280

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not react with GABA-A-R-Alpha4

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Gamma-aminobutyric acid receptor subunit alpha-6 (GABA(A) receptor subunit alpha-6)

UniProt Details

UniProt (Human): Q16445
UniProt (Immunogen Species): P16305

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Anti-GABA-A-R-Alpha6 Antibody FL490 Conjugate (N229A/32)

SKU: 75-388-FL490

Product Details

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