Anti-GABA-A-R, Delta Antibody FL490 Conjugate (N151/3)

Name: Anti-GABA-A-R, Delta Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-171-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-GABA(A)R, Delta mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N151/3. It detects mouse and rat GABA(A)R, Delta, and is purified by Protein A chromatography. It is great for use in ICC.

Species Reactivity

Mouse, Rat

Applications

ICC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-171-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

GABA(A)R, Delta

Target Description

Gamma-aminobutyric acid receptor subunit delta or Delta GABA-A receptor is encoded by the gene GABRD. GABAA receptors are members of the Cys-loop family of ligand-gated ion channels. GABA AR delta is a subunit of the pentameric GABA receptors where GABA is the major inhibitory neurotransmitter in the vertebrate brain and mediates neuronal inhibition by binding to the GABA receptor and opening an integral chloride channel. GABA AR delta is highly expressed in brain at the cell junction, synapse, postsynaptic cell membrane and cytoplasmic vesicle membrane. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N151/3

Isotype

IgG2a

Applications

ICC

Host Species

Mouse

Gene Name

Gabrd

Molecular Weight

55 kDa

Antigen

Synthetic peptide amino acids 15-34 (CTQPHHGARAMNDIGDYVGS, extracellular N-terminus) of rat GABA-A-R-Delta (accession number P18506)

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2939628

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Gamma-aminobutyric acid receptor subunit delta (GABA(A) receptor subunit delta)

UniProt Details

UniProt (Human): O14764
UniProt (Immunogen Species): P18506

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Anti-GABA-A-R, Delta Antibody FL490 Conjugate (N151/3)

SKU: 75-171-FL490

Product Details

Bulk Order Anti-GABA-A-R, Delta Antibody FL490 Conjugate

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