Anti-GFAP Recombinant Guinea Pig Chimeric mAb Biotin Conjugate (N206A/8)

Name: Anti-GFAP Recombinant Guinea Pig Chimeric mAb Biotin Conjugate
Brand: Antibodies Incorporated
SKU: 74-240-BTN
Price: 562.0 USD
Availability: InStock

Our guinea pig GFAP biotin conjugate recombinant antibody from Antibodies Incorporated is produced in-house from clone N206A/8. It detects drosophila, guinea pig, human, mouse, polar bear, and rat GFAP and is purified by affinity chromatography. KO validated. Works in ELISA, ICC, IHC, WB.

Anti-GFAP Recombinant Guinea Pig Chimeric mAb Biotin Conjugate

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Species Reactivity

Drosophila, Guinea Pig, Human, Mouse, Polar Bear, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Guinea Pig

Conjugates and Formulations

Unconjugated

490

550

594

650

Carrier-Free

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KO Validated

Trial Size

SKU: 74-240-BTN

Volume: 200 µL

Variant

Price:

$562.00

Quantity:

Ships: 1-5 business days

Product Details

Target

GFAP

Scientific Background

Glial fibrillary acidic protein (GFAP) is an intermediate filament with many different isoforms, and acts as a structural protein in the cytoskeleton. It is expressed in astrocytes in brain and is often used as an astrocyte marker. GFAP is believed to be involved in many CNS processes including cell communication and mitosis. GFAP has been found to be involved in Alexander disease and Wernicke's encephalopathy.

Format

Purified by affinity chromatography

Concentration

Lot dependent: provided at 0.3-0.5 mg/mL

Clonality

Recombinant

Clone

N206A/8

Isotype

IgG

Applications

ELISA, ICC, IHC, WB

Host Species

Guinea Pig

Gene Name

GFAP

Molecular Weight

50 kDa

Immunogen

Synthetic peptide amino acids 411-422 (KTVEMRDGEVIK) of human GFAP (accession number P14136)

Immunogen Species

Human

Species Reactivity

Drosophila, Guinea Pig, Human, Mouse, Polar Bear, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of our NeuroMab clone N206A/8 with guinea pig IgG heavy and light constant regions. As such this antibody retains the same binding performance as the original clone N206A/8 but can be detected using standard anti-guinea pig secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media and conjugated.

Buffer

1X PBS, 0.05% Sodium Azide pH 7.4

Conjugate

Biotin

Specificity

Cross-reacts with GFAP-R416W and other GFAP mutant proteins. Does not cross-react with other proteins (based on KO validation results).

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Synonyms

Glial fibrillary acidic protein (GFAP)

UniProt ID

P14136

Shipping

Shipped on ice packs

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Anti-GFAP Recombinant Guinea Pig Chimeric mAb Biotin Conjugate (N206A/8)

SKU: 74-240-BTN

Product Details

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