Anti-Homer1 Recombinant Chicken Chimeric mAb (L113/130)
Our chicken Anti-Homer1 recombinant monoclonal antibody is a chimeric antibody derived from NeuroMab clone L113/130. It detects human, mouse, and rat Homer1, and is purified by affinity chromatography. It is great for use in AT, ELISA, IHC, ICC, WB.






Representative section of formalin fixed, paraffin-embedded rat brain cerebellum region showing staining of Homer1 with anti-Homer1 recombinant chicken monoclonal antibody (green) (Cat No 78-454) at 1:100 dilution. The stained sections were mounted with FluoroshieldTM with DAPI and DABCO mounting medium (Cat No. AR-6505). DAPI nuclear stain (blue) shows cell nuclei. Anti-Homer1 stains the postsynaptic densities of the Purkinje cell dendrites in the molecular layer of the cerebellum. Magnification 100X.
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SKU: 78-454
Ships: 1-2 business days
Product Details
Homer1
Homer Scaffold Protein 1 is encoded by the gene HOMER1. Homer1 is a member of the Homer family of dendritic proteins. Homer1 is a postsynaptic density scaffolding protein which binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1, and SHANK3. HOMER1 is expressed in the skeletal muscle, heart, and brain. Diseases associated with HOMER1 include Phelan-Mcdermid Syndrome, bipolar disorder, autism, fragile x syndrome, and pervasive developmental disorder.
Purified by affinity chromatography
1 mg/mL
Recombinant
L113/130
IgY
AT, ELISA, ICC, IHC, WB
Chicken
Homer1 Vesl1
50 kDa
Fusion protein amino acids 121-363 (C-terminus) of mouse Homer1 (accession number Q9Z2Y3) produced recombinantly in E. Coli
Human, Mouse, Rat
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
This recombinant antibody is a chimeric antibody created by replacing the mouse heavy and light constant regions of clone L113/130 with chicken IgY heavy and light constant regions. As such this antibody retains the same binding performance as the original clone L113/130 but can be detected using standard anti-chicken secondary antibodies allowing flexibility for multiplexing applications. This antibody is expressed recombinantly in mammalian cells and then affinity purified from the cell culture media.
1X PBS, 0.05% Sodium Azide pH 7.4
WB: 1:500-1:1000
IHC: 1:100
ICC: 1:100
IHC: 1:100
ICC: 1:100
Unconjugated
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Shipped on ice packs
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