Our Anti-KA2 kainate receptor mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N279B/27. It is KO validated, detects mouse and rat KA2 kainate receptor, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Glutamate Ionotropic Receptor Kainate Type Subunit 5 is encoded by the gene GRIK5. GRIK5 is a member of the glutamate-gated ion channel (TC 1.A.10.1) family, GRIK5 subfamily. GRIK5 forms functional heteromeric kainate-preferring ionic channels with the subunits encoded by related gene family members. GRIK5 is highly expressed in the cerebral cortex, pyriform cortex, caudate-putamen, hippocampal complex, medial habenulata, and granule cell layer of the cerebellum. GRIK5 is weakly expressed in the globus pallidus, thalamus, colliculi, and the reticular thalamic nucleus. Diseases associated with GRIK5 include Schizophrenia and Autosomal Recessive Non-Syndromic Intellectual Disability.
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
N279B/27
IgG2a
ICC, IHC
Mouse
Grik5
110 kDa
Fusion protein amino acids 825-979 (cytoplasmic C-terminus) of rat KA2 kainate receptor (accession number Q63273) produced recombinantly in E. Coli
Mouse, Rat
AB_2940212
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL490 Ex: 491 nm, Em: 515 nm
Does not cross-react with KA1
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
