Anti-Kv1.1 K+ Channel (External) Antibody (BSA and Azide free) (K36/15)

Name: Anti-Kv1.1 K+ Channel (External) Antibody (BSA and Azide free)
Brand: NeuroMab
SKU: 75-105-CF
Price: 475.0 USD
Availability: InStock

Our carrier-free Anti-Kv1.1 K+ channel (external) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K36/15. It is KO validated, detects mouse and rat Kv1.1 K+ channel (external), and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Species Reactivity

Mouse, Rat

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Conjugates and Formulations

Unconjugated

490

550

594

650

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Data Sheet

KO Validated

SKU: 75-105-CF

Volume: 100 µL

Variant

Price:

$475.00

Quantity:

Product Details

Target

Kv1.1 K+ channel (external)

Target Description

Potassium Channel Kv1.1or Kcna1 is a member of the Shaker potassium channel family. Kv1.1 is expressed in the brain, CNS and in the kidney. Potassium channels form homotetrameric and heterotetrameric channels in the membrane with various other related proteins, including KCNA2, KCNA4, KCNA5, KCNA6, KCNA7. Kv1.1 is involved with the regulation of cellular functions and the control of neuronal excitability. Mutations in Kv1.1 are associated with Episodic ataxia type 1 and epilepsy.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

K36/15

Isotype

IgG2b

Applications

ELISA, ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcna1

Molecular Weight

56 kDa (could be 65-85 kDa depending on glycosylation)

Antigen

Synthetic peptide amino acids 191-208 (ELKDDKDFTGTIHRIDNTC, extracellular domain) of rat Kv1.1 (accession number P10499)

Species Reactivity

Mouse, Rat

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and buffer exchanged into 1X PBS. Purified mAbs are >90% specific antibody.

Buffer

PBS

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Potassium voltage-gated channel subfamily A member 1 (RBKI) (RCK1) (Voltage-gated potassium channel subunit Kv1.1)

UniProt ID

P10499

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Anti-Kv1.1 K+ Channel (External) Antibody (BSA and Azide free) (K36/15)

SKU: 75-105-CF

Product Details

Bulk Order Anti-Kv1.1 K+ Channel (External) Antibody (BSA and Azide free)

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