Anti-Kv4.2 Potassium Channel Antibody FL490 Conjugate (L28/4)

Name: Anti-Kv4.2 Potassium Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-361-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-Kv4.2 potassium channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L28/4. It is KO validated, detects human, mouse, and rat Kv4.2 potassium channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

KO Validated

SKU: 75-361-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Kv4.2 potassium channel

Target Description

Potassium voltage-gated channel subfamily D member 2 or Kv4.2 potassium channel subunit is encoded by the gene KCND2. Kv4.2 is an alpha subunit of the voltage-gated potassium channel (Shal) family and mediates transmembrane potassium transport in excitable membranes. Kv4.2 is an integral membrane protein that combines to form tetramers. Kv4.2 is detected in the heart and brain. In brain it is found at the cell junction, synapse, postsynaptic cell membrane. Diseases associated with this gene include Cycloplegia and early myoclonic encephalopathy.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

L28/4

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnd2

Molecular Weight

70 kDa

Antigen

Fusion protein amino acids 471-630 (cytoplasmic C-terminus) of rat Kv4.2 (accession number Q63881) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2940208

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with Kv4.3 (based on KO validation results)

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Potassium voltage-gated channel subfamily D member 2 (RK5) (Shal1) (Voltage-gated potassium channel subunit Kv4.2)

UniProt Details

UniProt (Human): Q9NZV8
UniProt (Immunogen Species): Q63881

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Anti-Kv4.2 Potassium Channel Antibody FL490 Conjugate (L28/4)

SKU: 75-361-FL490

Product Details

Bulk Order Anti-Kv4.2 Potassium Channel Antibody FL490 Conjugate

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