Anti-LRRTM2 Antibody (N209C/35)

Name: Anti-LRRTM2 Antibody
Brand: NeuroMab
SKU: 75-364
Price: 329.0 USD
Availability: InStock

Our Anti-LRRTM2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N209C/35. It is KO validated, detects human, mouse, and rat LRRTM2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Immunoblot against crude brain membrane preparations from adult rat (RBM) or extracts of COS cells transiently transfected with Myc- tagged LRRTM1, LRRTM2 or untagged Kv2.1 plasmid probed with N209C/35 (left), K89/34 (middle) or N52A/42 (right) TC supe.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

Go to Full Product Details

Data Sheet

KO Validated

SKU: 75-364

Volume: 100 µL

Variant

Price:

$329.00

Quantity:

Product Details

Target

LRRTM2

Target Description

Leucine Rich Repeat Transmembrane Neuronal 2 is encoded by the gene LRRTM2. LRRTM2 is a member of the LRRTM family. LRRTM2 is involved in the development and maintenance of excitatory synapses in the vertebrate nervous system. LRRTM2 regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. LRRTM2 is expressed in neuronal tissues. Diseases associated with LRRTM2 include Histrionic Personality Disorder.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N209C/35

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

LRRTM2 KIAA0416 LRRN2

Molecular Weight

80 kDa (and larger due to glycosylation)

Antigen

Synthetic peptide amino acids 475-489 (MSNMSDQGPYNEYEP, cytoplasmic C-terminus) of human LRRTM2 (accession number O43300)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2315886

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with LRRTM1

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Leucine-rich repeat transmembrane neuronal protein 2 (Leucine-rich repeat neuronal 2 protein)

UniProt Details

UniProt (Human): O43300
UniProt (Immunogen Species): O43300

Product Specific References for Applications and Species

Immunocytochemistry: Rat

Immunocytochemistry: Rat
PMID	Dilution	Publication
25981034	not listed	Calafate, S., et al. 2015. Synaptic Contacts Enhance Cell-to-Cell Tau Pathology Propagation. Cell Reports, 1176-1183.

Recover password

Create my account

Anti-LRRTM2 Antibody (N209C/35)

SKU: 75-364

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-LRRTM2 Antibody

Related Products

Recently Viewed