Anti-Mitofusin-1 Antibody FL490 Conjugate (N111/24)

Name: Anti-Mitofusin-1 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-162-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-Mitofusin-1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N111/24. It is KO validated, detects mouse and rat Mitofusin-1, and is purified by Protein A chromatography. It is great for use in ICC.

Species Reactivity

Mouse, Rat

Applications

ICC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

KO Validated

SKU: 75-162-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

Mitofusin-1

Target Description

Mitofusin 1, or transmembrane GTPase Mfn1 (MFN1) is a mitochondrial membrane protein with GTPase activity that functions to aid mitochondrial clustering and fusion. It may also play a role in mitochondrial metabolism. It is expressed in the outer membrane of mitochondria in many tissues, including heart and testis. Diseases associated with MFN1 include Optic Atrophy 1 and Autosomal Recessive Spastic Paraplegia .

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N111/24

Isotype

IgG1

Applications

ICC

Host Species

Mouse

Gene Name

Mfn1

Molecular Weight

80 kDa

Antigen

Fusion protein amino acids 350-580 of mouse Mitofusin-1 (accession number Q811U4) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2939600

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity against Mitofusin-2

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Mitofusin-1 (EC 3.6.5.-) (Transmembrane GTPase MFN1)

UniProt Details

UniProt (Human): Q811U4
UniProt (Immunogen Species): Q811U4

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Anti-Mitofusin-1 Antibody FL490 Conjugate (N111/24)

SKU: 75-162-FL490

Product Details

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