Anti-Neuroligin-1 Antibody FL490 Conjugate (N97A/31)

Name: Anti-Neuroligin-1 Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-160-FL490
Price: 474.0 USD
Availability: InStock

Our Anti-Neuroligin-1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N97A/31. It is KO validated, detects mouse and rat Neuroligin-1, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Chicken, Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

KO Validated

SKU: 75-160-FL490

Volume: 200 µL

Variant

Price:

$474.00

Quantity:

Product Details

Target

Neuroligin-1

Target Description

Neuroligin 1 is a member of a large family of alternatively sliced proteins located at the post synaptic surface in the central nervous system, and stains as a post synaptic marker. Neuroligin 1 is involved in cell-cell-interactions by binding to neurexin family members and other postsynaptic proteins to localize receptors and channels in the postsynaptic density. Suggested roles for Neuroligin 1 include synapse function and synaptic signal transmission and maintaining synapse integrity. Mutations in Neuroligans have been implicated in autism and other cognitive disorders.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N97A/31

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Nlgn1

Molecular Weight

120 kDa

Antigen

Fusion protein amino acids 718-843 (intracellular C-terminus) of rat Neuroligin-1 (accession number NP_446320) produced recombinantly in E. Coli

Species Reactivity

Chicken, Human, Mouse, Rat

Antibody Registry ID

AB_2939592

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

Does not cross-react with Neuroligin-2, -3, -4 or -4*

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Neuroligin-1 (Neuroligin I)

UniProt Details

UniProt (Human): Q8N2Q7
UniProt (Immunogen Species): Q62765

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Anti-Neuroligin-1 Antibody FL490 Conjugate (N97A/31)

SKU: 75-160-FL490

Product Details

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