Anti-NGL-1/LRRC4C Antibody (N49A/21)

Name: Anti-NGL-1/LRRC4C Antibody
Brand: NeuroMab
SKU: 75-108
Price: 319.0 USD
Availability: InStock

Our Anti-NGL-1/LRRC4C mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N49A/21. It detects human, mouse, and rat NGL-1/LRRC4C, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Adult rat brain membrane (RBM) and transfected cell immunoblot: extracts of RBM and COS cells transiently transfected with Myc-tagged NGL-1, NGL-2, NGL-3 or untagged Kv2.1 plasmid and probed with N49A/21 (left and middle) or K89/34 (right) TC supe.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC, IP, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-108

Product Details

Target

NGL-1/LRRC4C

Target Description

Leucine Rich Repeat Containing 4C is encoded by the gene LRRC4C. LRRC4C may promote neurite outgrowth of developing thalamic neurons. LRRC4C is expressed in the brain. Diseases associated with LRRC4C include Extragonadal Seminoma and Chief Cell Adenoma.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N49A/21

Isotype

IgG1

Applications

ICC, IHC, IP, WB

Host Species

Mouse

Gene Name

LRRC4C KIAA1580 NGL1 UNQ292/PRO331

Molecular Weight

100 kDa

Antigen

Fusion protein amino acids 551-640 of human NGL-1 (accession number NP_065980) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2137628

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.36

Dilution Ranges

ICC: 1:500

Conjugate

Unconjugated

Specificity

No cross-reactivity against NGL-2 or NGL-3

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Leucine-rich repeat-containing protein 4C (Netrin-G1 ligand) (NGL-1)

UniProt Details

UniProt (Human): Q9HCJ2
UniProt (Immunogen Species): Q9HCJ2

Product Specific References for Applications and Species

Immunocytochemistry: Human

Immunocytochemistry: Human
PMID	Dilution	Publication
22922712	1:500	Ricciardi S, et al. 2012. CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.. Nature Cell Biology, 911-923.

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Anti-NGL-1/LRRC4C Antibody (N49A/21)

SKU: 75-108

Product Details

Product Specific References for Applications and Species

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