Our Anti-Pan-Kvbeta K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K40/17. It detects human, mouse, and rat Pan-Kvbeta K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
The ß subunits of voltage-gated potassium channels are members of the potassium channel, voltage-gated, shaker-related subfamily. Kvβs are cytoplasmic subunits that modulate the characteristics of the membrane spanning, channel-forming alpha-subunits. Beta subunits can promote the closure of channels or enhance channel activity depending on other channel proteins. There are three ß subunits (Kvß1, Kvß2, Kvß3) which are coded by three different genes. Additionally, there is alternative splicing of these three genes, further diversifying the functions and tissue expression of the family.
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
K40/17
IgG2a
ICC, IHC
Mouse
Kcnab1 Kvb1 Kcnab3 Ckbeta3 Kcnab2 Ckbeta2 Kcnb3
30-45 kDa
Fusion protein amino acids 1-401 (full-length) of rat Kv1 (accession number P63144) produced recombinantly in E. Coli
Human, Mouse, Rat
AB_2939398
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL594 Ex: 594 nm, Em: 615 nm
No cross-reactivity reported
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
