Anti-Pannexin-2 Antibody (N121A/1)

Name: Anti-Pannexin-2 Antibody
Brand: NeuroMab
SKU: 75-212
Price: 319.0 USD
Availability: InStock

Our Anti-Pannexin-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N121A/1. It detects rat Pannexin-2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Adult rat hippocampus immunohistochemistry.

Species Reactivity

Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-212

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

Pannexin-2

Target Description

Pannexin 2 is encoded by the gene PANX2. PANX2 is a member of the pannexin family. PANX2 combines with pannexin 1 to form cell type-specific gap junctions with distinct properties. PANX2 is expressed in the eye, thyroid, prostate, kidney, liver, and central nervous system. Diseases associated with PANX2 include Oculodentodigital Dysplasia and Chronic Closed-Angle Glaucoma.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N121A/1

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Panx2 Px2

Molecular Weight

70 kDa

Antigen

Fusion protein amino acids 11-664 (all but first 10 amino acids, encompassing extracellular and cytoplasmic domains) of rat Pannexin-2 (accession number P60571) produced recombinantly in E. Coli

Species Reactivity

Rat

Antibody Registry ID

AB_10673510

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with Pannexin-1 or Pannexin-3

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Pannexin-2

UniProt Details

UniProt (Human): Q96RD6
UniProt (Immunogen Species): P60571

Product Specific References for Applications and Species

Immunocytochemistry: Rat
Immunohistochemistry: Mouse
Immunogold: Rat
Western Blot: Mouse | Rat

Immunocytochemistry: Rat
PMID	Dilution	Publication
30862038	2ug/ml	Le Vasseur, M., et al. 2019. Pannexin 2 Localizes at ER-Mitochondria Contact Sites. Cancers, 343.

Immunohistochemistry: Mouse
PMID	Dilution	Publication
25505382	1:50	Le Vasseur, M., et al. 2014. Pannexin 2 protein expression is not restricted to the CNS.. Frontiers in cellular neuroscience, 392.

Immunogold: Rat
PMID	Dilution	Publication
30862038	5ug/ml	Le Vasseur, M., et al. 2019. Pannexin 2 Localizes at ER-Mitochondria Contact Sites. Cancers, 343.

Western Blot: Mouse
PMID	Dilution	Publication
25505382	1:200	Le Vasseur, M., et al. 2014. Pannexin 2 protein expression is not restricted to the CNS.. Frontiers in cellular neuroscience, 392.

Western Blot: Rat
PMID	Dilution	Publication
30862038	4ug/ml	Le Vasseur, M., et al. 2019. Pannexin 2 Localizes at ER-Mitochondria Contact Sites. Cancers, 343.

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Anti-Pannexin-2 Antibody (N121A/1)

SKU: 75-212

Product Details

Product Specific References for Applications and Species

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