Anti-PSD-95 Antibody (K28/43)

917 Citations

Our Anti-PSD 95 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K28/43. It is KO validated, detects chicken, human, mouse, non-human primate, and rat PSD 95, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Immunofluorescence staining of cultured rat hippocampal neurons with K28/43 (green) and K57/1 (red, Kv4.2).
Electron micrograph of K28/43 hippocampal labelling using a post-embedding immunogold method. Immunoparticles (arrows) are seen in the postsynaptic densities of dendritic spines (s) forming asymmetrical synapses with axon terminals (b). Scale bar = 200 nm. Image courtesy of Rafael Lujan (Universidad de Castilla-La Mancha).
Adult rat brain immunohistochemistry.
Immunoblot against adult rat brain membranes (RBM) and adult mouse hippocampal membranes (MHM) from PSD-95 and -93 knockout (KO) mice probed with K28/43 (left) or K28/86 (right) TC supe. Mouse samples courtesy of Richard Huganir (Johns Hopkins University, Howard Hughes Medical Institute).
Western blot of total homogenate (H) and TIF fraction from rat hippocampal neurons treated with vehicle (CTRL) or NMDA. Image from publication CC-BY-4.0. PMID: 35613587
Immunolabelling of fixed primary rat hippocampal neurons for SENP1 and PSD95. Image from publication CC-BY-4.0. PMID: 35739402
Double staining of GluA1 (red) and PSD-95 (green) in P12 MNTB neurons of control (left) and Nlgn3 KO (right) mice. Image from publication CC-BY-4.0. PMID: 35704570
Western blot analysis of PSD-95 and synaptophysin protein in the hippocampus region of AD mice. Image from publication CC-BY-4.0. PMID: 35701825
Expression levels of ARID1B protein in WT mouse brains at E18, P0, P7, P14, P21, P28, P35, and P42, as determined by immunoblot analysis of whole-brain lysates. PSD-95, an abundant excitatory postsynaptic density protein, is shown for comparison. The full-length blot was divided into three parts for immunoblotting with different antibodies. Similar results were obtained from three independent experiments. Image from publication CC-BY-4.0. PMID: 36030255
Immunolabeling of Synapsin 1 (SYN1) and PSD95-positive cells (green and red respectively) within MAP2+ neurons (white) in ight-week-old human brain cortical organoids (BCO) infected at MOI 2.5 and treated with vehicle (Veh) or 20μM Sofosbuvir (SOF). Image from publication CC-BY-4.0. PMID:36327326
Representative images of HEK293 cells transfected with different combinations of PSD95( cat. 75-028, 1:2000), GluN2A-CTD, WT, and R9A Rph3A. Image from publication CC-BY-4.0. PMID:36693856
Primary cultures of rat hippocampal neurons were treated at DIV9 with either 2 μg/μl sOligo or PBS and analyses were performed at DIV16. Scaffolding protein Rph3A and PSD-95 (cat. 75-028, 1:1000) were evaluated by Western blot in TIF from sOligo- or PBS-neurons. Image from publication CC-BY-4.0. PMID:37009450
Representative confocal images of mouse cortical neurons using DAPI, MAP2, and PSD95 (cat. 75-028, 1:1000) in control conditions (upper images) and treated with DAPT inhibitor (lower images). Image from publication CC-BY-4.0. PMID:37059474
Effects of Ank2 cKO on the localization of Kv7.3 at excitatory and inhibitory synapses in cultured mouse cortical neurons (DIV 17). Note that the colocalization, determined by colocalized areas, between Kv7.3 (green) and PSD-95 (cat. 75-028, 1:1000; red) (an excitatory synapse marker) is not changed, whereas the mean intensity of Kv7.3 at the colocalized area is moderately decreased. Image from publication CC-BY-4.0. PMID:37321992
Immunostaining of Cas9-expressing cortical neuronal cultures transduced with mock lentiviral vectors (control, left), lentiviral vectors carrying gRNAs to delete Pcdh15 (Pcdh15 Δex6, middle), and sPcdh15-expressing vectors (sPcdh15, right) with the neuronal markers PSD95 (cat. 75-028) and MAP2. Upper: PSD95-expressing puncta. Middle: overlay of PSD95 and MAP2. Lower: magnification of middle panel. Image from publication CC-BY-4.0. PMID:37595869
Dissociated hippocampal neurons isolated from P0 Emx1Cre:R26P1 and Emx1Cre;R26P1R203W mice were processed for confocal imaging at DIV18 to detect MAP2 (magenta), HA-tagged PACS1 or PACS1R203W (pseudocolored green), PSD95 (cat. 75-028, 1:250; pseudocolored red) and DAPI (blue). Image from publication CC-BY-4.0. PMID:37848409
DIV18 neurons prepared from WT C57BL/6 mice were processed for confocal imaging to detect endogenous HDAC6 (green), PACS1 (red), and PSD95 (cat. 75-028, 1:250; blue), and the fluorescent signal from the indicated spine (yellow line) was measured (Nikon Elements). Image from publication CC-BY-4.0. PMID:37848409
Immunofluorescences against PSD95 cat. 75-028) and Synaptophysin in wild-type, FL, and FL1-injected mouse neurons. Image from publication CC-BY-4.0. PMID:37957716
Single confocal images of wildtype (top), heterozygote (middle) and mutant (bottom), showing the colocalization of vGlut1+ boutons (blue) and PSD95+ clusters (cat. 75-028ed) onto VIP+ proximal dendrites (white outline) (yellow arrows) at P45. Image from publication CC-BY-4.0. PMID:38201256
Immunofluorescence staining of cultured rat hippocampal neurons with K28/43 (green) and K57/1 (red, Kv4.2).
Immunofluorescence staining of cultured rat hippocampal neurons with K28/43 (green) and K57/1 (red, Kv4.2).
Electron micrograph of K28/43 hippocampal labelling using a post-embedding immunogold method. Immunoparticles (arrows) are seen in the postsynaptic densities of dendritic spines (s) forming asymmetrical synapses with axon terminals (b). Scale bar = 200 nm. Image courtesy of Rafael Lujan (Universidad de Castilla-La Mancha).
Adult rat brain immunohistochemistry.
Immunoblot against adult rat brain membranes (RBM) and adult mouse hippocampal membranes (MHM) from PSD-95 and -93 knockout (KO) mice probed with K28/43 (left) or K28/86 (right) TC supe. Mouse samples courtesy of Richard Huganir (Johns Hopkins University, Howard Hughes Medical Institute).
Western blot of total homogenate (H) and TIF fraction from rat hippocampal neurons treated with vehicle (CTRL) or NMDA. Image from publication CC-BY-4.0. PMID: 35613587
Immunolabelling of fixed primary rat hippocampal neurons for SENP1 and PSD95. Image from publication CC-BY-4.0. PMID: 35739402
Double staining of GluA1 (red) and PSD-95 (green) in P12 MNTB neurons of control (left) and Nlgn3 KO (right) mice. Image from publication CC-BY-4.0. PMID: 35704570
Western blot analysis of PSD-95 and synaptophysin protein in the hippocampus region of AD mice. Image from publication CC-BY-4.0. PMID: 35701825
Expression levels of ARID1B protein in WT mouse brains at E18, P0, P7, P14, P21, P28, P35, and P42, as determined by immunoblot analysis of whole-brain lysates. PSD-95, an abundant excitatory postsynaptic density protein, is shown for comparison. The full-length blot was divided into three parts for immunoblotting with different antibodies. Similar results were obtained from three independent experiments. Image from publication CC-BY-4.0. PMID: 36030255
Immunolabeling of Synapsin 1 (SYN1) and PSD95-positive cells (green and red respectively) within MAP2+ neurons (white) in ight-week-old human brain cortical organoids (BCO) infected at MOI 2.5 and treated with vehicle (Veh) or 20μM Sofosbuvir (SOF). Image from publication CC-BY-4.0. PMID:36327326
Representative images of HEK293 cells transfected with different combinations of PSD95( cat. 75-028, 1:2000), GluN2A-CTD, WT, and R9A Rph3A. Image from publication CC-BY-4.0. PMID:36693856
Primary cultures of rat hippocampal neurons were treated at DIV9 with either 2 μg/μl sOligo or PBS and analyses were performed at DIV16. Scaffolding protein Rph3A and PSD-95 (cat. 75-028, 1:1000) were evaluated by Western blot in TIF from sOligo- or PBS-neurons. Image from publication CC-BY-4.0. PMID:37009450
Representative confocal images of mouse cortical neurons using DAPI, MAP2, and PSD95 (cat. 75-028, 1:1000) in control conditions (upper images) and treated with DAPT inhibitor (lower images). Image from publication CC-BY-4.0. PMID:37059474
Effects of Ank2 cKO on the localization of Kv7.3 at excitatory and inhibitory synapses in cultured mouse cortical neurons (DIV 17). Note that the colocalization, determined by colocalized areas, between Kv7.3 (green) and PSD-95 (cat. 75-028, 1:1000; red) (an excitatory synapse marker) is not changed, whereas the mean intensity of Kv7.3 at the colocalized area is moderately decreased. Image from publication CC-BY-4.0. PMID:37321992
Immunostaining of Cas9-expressing cortical neuronal cultures transduced with mock lentiviral vectors (control, left), lentiviral vectors carrying gRNAs to delete Pcdh15 (Pcdh15 Δex6, middle), and sPcdh15-expressing vectors (sPcdh15, right) with the neuronal markers PSD95 (cat. 75-028) and MAP2. Upper: PSD95-expressing puncta. Middle: overlay of PSD95 and MAP2. Lower: magnification of middle panel. Image from publication CC-BY-4.0. PMID:37595869
Dissociated hippocampal neurons isolated from P0 Emx1Cre:R26P1 and Emx1Cre;R26P1R203W mice were processed for confocal imaging at DIV18 to detect MAP2 (magenta), HA-tagged PACS1 or PACS1R203W (pseudocolored green), PSD95 (cat. 75-028, 1:250; pseudocolored red) and DAPI (blue). Image from publication CC-BY-4.0. PMID:37848409
DIV18 neurons prepared from WT C57BL/6 mice were processed for confocal imaging to detect endogenous HDAC6 (green), PACS1 (red), and PSD95 (cat. 75-028, 1:250; blue), and the fluorescent signal from the indicated spine (yellow line) was measured (Nikon Elements). Image from publication CC-BY-4.0. PMID:37848409
Immunofluorescences against PSD95 cat. 75-028) and Synaptophysin in wild-type, FL, and FL1-injected mouse neurons. Image from publication CC-BY-4.0. PMID:37957716
Single confocal images of wildtype (top), heterozygote (middle) and mutant (bottom), showing the colocalization of vGlut1+ boutons (blue) and PSD95+ clusters (cat. 75-028ed) onto VIP+ proximal dendrites (white outline) (yellow arrows) at P45. Image from publication CC-BY-4.0. PMID:38201256

Chicken, Human, Mouse, Non-Human Primate, Rat
ICC, IHC, IP, WB
Mouse
490
550
594
650

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Data Sheet
KO Validated KO Validated Trial Size Trial Size

SKU: 75-028

Volume: 100 µL
1-2 business days
Price:
$374.00

Product Specific References for Applications and Species

  • Immunocytochemistry: Chicken | Human | Mouse | Rat
  • Immunohistochemistry: Chicken | Human | Mouse | Non-Human Primate | Rat
  • Immunoprecipitation: Human | Mouse | Rat
  • Microfluidic Assay: Mouse
  • PLA: Mouse
  • STED: Mouse
  • STORM: Mouse
  • Western Blot: Chicken | Human | Mouse | Non-Human Primate | Rat
    • Immunocytochemistry: Chicken
    PMID Dilution Publication
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    Immunocytochemistry: Human
    PMID Dilution Publication
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    382147681:500Kysilov, B., et al. 2024. Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids. Cellular and Molecular Life Sciences, 36.
    366938561:2000Yang, L., et al. 2023. Rabphilin-3A Undergoes Phase Separation to Regulate GluN2A Mobility and Surface Clustering. Nature Communications, 379.
    364178731:1000Murtaza, N., et al. 2022. Neuron-Specific Protein Network Mapping Of Autism Risk Genes Identifies Shared Biological Mechanisms And Disease-Relevant Pathologies. Cell Reports, 111678.
    363851681:1000Adams, J.W., et al. 2022. Impact Of Alcohol Exposure On Neural Development And Network Formation In Human Cortical Organoids. Molecular Psychiatry, .
    363273261:500Mesci, P., et al. 2022. SARS-CoV-2 infects human brain organoids causing cell death and loss of synapses that can be rescued by treatment with Sofosbuvir. PLoS Biology, e3001845.
    359872031:300Traxler, L., et al. 2022. Warburg-like metabolic transformation underlies neuronal degeneration in sporadic Alzheimer's disease. Cell Metabolism, 1248-1263.
    358771031:500Böhnke, L., et al. 2022. Chemical Replacement of Noggin with Dorsomorphin Homolog 1 for Cost-Effective Direct Neuronal Conversion. Cellular Reprogramming, .
    354431701:200Müller, J.A., et al. 2022. A Presynaptic Phosphosignaling Hub for Lasting Homeostatic Plasticity. Cell Reports, 110696.
    349574781:1000Avansini, S.A., et al. 2021. Junctional instability in neuroepithelium and network hyperexcitability in a focal cortical dysplasia human model. Brain: A Journal of Neurology, .
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    34113010not listedMay, H.J., et al. 2021. Truncating variants in the SHANK1 gene are associated with a spectrum of neurodevelopmental disorders. Genetics in Medicine, 1912-1921.
    315911571:50Winden, K.D., et al. 2019. Biallelic Mutations in TSC2 Lead to Abnormalities Associated with Cortical Tubers in Human iPSC-Derived Neurons. Journal of Neuroscience, 9294-9305.
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    Immunocytochemistry: Mouse
    PMID Dilution Publication
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    384726491:100Campos, J., et al. 2024. Liprin-α proteins are master regulators of human presynapse assembly. Nature Neuroscience, .
    382136271:300Clavet-Fournier, V., et al. 2024. Pre- and postsynaptic nanostructures increase in size and complexity after induction of long-term potentiation. iScience, 108679.
    37957716not listedBustos, FJ, et al. 2023. Removal of a partial genomic duplication restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer. BMC biology, 232.
    377930461:500Smith, CS, et al. 2023. Enhanced Neuron Growth and Electrical Activity by a Supramolecular Netrin-1 Mimetic Nanofiber. ACS Nano, 19887-19902.
    376540261:200Abdel-Ghani, M, et al. 2023. Plk2 promotes synaptic destabilization through disruption of N-cadherin adhesion complexes during homeostatic adaptation to hyperexcitation. Journal of Neurochemistry, 0.
    37595869not listedDarwish, M, et al. 2023. Neuronal SAM68 differentially regulates alternative last exon splicing and ensures proper synapse development and function. The Journal of Biological Chemistry, 105168.
    373219921:1000Oh, H, et al. 2023. Kv7/KCNQ Potassium Channels in Cortical Hyperexcitability and Juvenile Seizure-related Death in Ank2-mutant Mice. Nature Communications, 3547.
    373056961:1000Opland, C, et al. 2023. Activity-dependent tau cleavage by caspase-3 promotes neuronal dysfunction and synaptotoxicity. iScience, 106905.
    372619531:500Bygrave, AM, et al. 2023. Btbd11 supports cell-type-specific synaptic function. Cell reports, 112591.
    370594741:1000Carús-Cadavieco, M., et al. 2023. Cognitive Decline in Diabetic Mice Predisposed to Alzheimer's Disease is Greater Than in Wild Type. Life Science Alliance, e202201789.
    36803960not listedMaruo, T., et al. 2023. s-Afadin Binds to MAGUIN/Cnksr2 and Regulates the Localization of the AMPA Receptor and Glutamatergic Synaptic Response in Hippocampal Neurons. The Journal of Biological Chemistry, 103040.
    365733491:500Huang, Y.J., et al. 2022. Astrocytic Aryl Hydrocarbon Receptor Mediates Chronic Kidney Disease-Associated Mental Disorders Involving GLT1 Hypofunction and Neuronal Activity Enhancement in the Mouse Brain. Glia, .
    364585271:300Nozawa, O., et al. 2022. A Novel Necl-2/3-mediated Mechanism for Tripartite Synapse Formation. Development, .
    359705641:200Joshi, D.C., et al. 2022. Tripartite Crosstalk Between Cytokine IL-1β, NMDA-R and Misplaced Mitochondrial Anchor in Neuronal Dendrites is a Novel Pathway for Neurodegeneration in Inflammatory Diseases. The Journal of Neuroscience, 7318-7329.
    Immunocytochemistry: Rat
    PMID Dilution Publication
    388190941:200Zhang, X, et al. 2024. Daphnetin protects neurons in an Alzheimer disease mouse model and normal rat neurons by inhibiting BACE1 activity and activating the Nrf2/HO-1 pathway. Journal of Neuropathology and Experimental Neurology, 0.
    386305751:500Cortese, GP, et al. 2024. ZCCHC17 knockdown phenocopies Alzheimer's disease-related loss of synaptic proteins and hyperexcitability. Journal of Neuropathology and Experimental Neurology, 0.
    385525561:200Lee, J, et al. 2024. Amyloid precursor protein combinatorial phosphorylation code regulates AMPA receptor removal during distinct forms of synaptic plasticity. Biochemical and Biophysical Research Communications, 149803.
    36969554not listedPiguel, N.H., et al. 2023. Palmitoylation Controls the Stability of 190 kDa Ankyrin-G in Dendritic Spines and is Regulated by ZDHHC8 and Lithium. Frontiers in Molecular Neuroscience, 1144066.
    369193351:200Lee, H.J., et al. 2023. Reelin and APP Cooperatively Modulate Dendritic Spine Formation In Vitro and In Vivo. Experimental Neurobiology, 42-55.
    366466911:300Scheefhals, N., et al. 2023. mGluR5 is Transiently Confined in Perisynaptic Nanodomains to Shape Synaptic Function. Nature Communications, 244.
    359310521:1000Kozlova, A., et al. 2022. Loss of function of OTUD7A in the schizophrenia- associated 15q13.3 deletion impairs synapse development and function in human neurons. American Journal of Human Genetics, 1500-1519.
    357394021:500Pronot, M., et al. 2022. Bidirectional Regulation of Synaptic SUMOylation by Group 1 Metabotropic Glutamate Receptors. Cellular and Molecular Life Sciences, 378.
    35248787not listedRiechers, S.P., et al. 2022. Neurons undergo pathogenic metabolic reprogramming in models of familial ALS. Molecular metabolism, 101468.
    351776161:200Hruska, M., et al. 2022. Nanoscale rules governing the organization of glutamate receptors in spine synapses are subunit specific. Nature communications, 920.
    344171701:200Ramsey, A.M., et al. 2021. Subsynaptic positioning of AMPARs by LRRTM2 controls synaptic strength. Science Advances, eabf3126.
    336332811:1000Iqbal, F., et al. 2021. A synthetic peptide rescues rat cortical neurons from anesthetic-induced cell death, perturbation of growth and synaptic assembly. Scientific Reports, 4567.
    33568460not listedJeong, J., et al. 2021. CaMKII Phosphorylation Regulates Synaptic Enrichment of Shank3. eNeuro, .
    30233305not listedJin, C., et al. 2021. Integrative Brain Transcriptome Analysis Reveals Region-Specific and Broad Molecular Changes in Shank3-Overexpressing Mice. Frontiers in Molecular Neuroscience, 250.
    32801157not listedCulotta, L., et al. 2020. SULT4A1 Modulates Synaptic Development and Function by Promoting the Formation of PSD-95/NMDAR Complex. Journal of Neuroscience, 7013-7026.
    32275651not listedWillems, J., et al. 2020. ORANGE: A CRISPR/Cas9-based genome editing toolbox for epitope tagging of endogenous proteins in neurons. PLoS Biology, e3000665.
    320666981:1000Erli, F., et al. 2020. Estradiol reverses excitatory synapse loss in a cellular model of neuropsychiatric disorders. Translational Psychiatry, 16.
    Immunohistochemistry: Chicken
    PMID Dilution Publication
    210315601:1000Wahlin, K.J., et al. 2010. Alternative splicing of neuroligin and its protein distribution in the outer plexiform layer of the chicken retina.. Journal of Comparative Neurology, 4938-62.
    Immunohistochemistry: Human
    PMID Dilution Publication
    383615351:50Majumder, J, et al. 2024. Human induced pluripotent stem cell-derived planar neural organoids assembled on synthetic hydrogels. Journal of tissue engineering, 20417314241230633.
    371954491:100Maroto, AF, et al. 2023. The vestibular calyceal junction is dismantled following subchronic streptomycin in rats and sensory epithelium stress in humans. Archives of toxicology, 1943-1961.
    333770841:500Ryan, S.K., et al. 2020. Protocol for Tri-culture of hiPSC-DerivedNeurons, Astrocytes, and Microglia. Cell Press, 100190.
    Immunohistochemistry: Mouse
    PMID Dilution Publication
    391465031:500Pavešković, M., et al. 2024. Alzheimer's disease risk gene CD2AP is a dose-sensitive determinant of synaptic structure and plasticity. Human Molecular Genetics, .
    391290071:200Chae, S., et al. 2024. The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta. Journal of Neuroinflammation, 200.
    391280141:500Wang, L., et al. 2024. Amitriptyline protects afferent synapses in the cochlea against excitotoxic trauma in vitro. The FEBS Journal, .
    391033181:200Han, X., et al. 2024. Multiplexed volumetric CLEM enabled by scFvs provides insights into the cytology of cerebellar cortex. Nature Communications, 6648.
    389260891:500Candelas Serra, M, et al. 2024. Characterization of mice carrying a neurodevelopmental disease-associated GluN2B(L825V) variant. The Journal of neuroscience : the official journal of the Society for Neuroscience, .
    387839021:50Robinson, K, et al. 2024. Mapping proteomic composition of excitatory postsynaptic sites in the cerebellar cortex. Frontiers in Molecular Neuroscience, 1381534.
    387364831:100Matsumoto, Y, et al. 2024. Slitrk4 is required for the development of inhibitory neurons in the fear memory circuit of the lateral amygdala. Frontiers in Molecular Neuroscience, 1386924.
    38552924not listedGillani, RL, et al. 2024. Instability of excitatory synapses in experimental autoimmune encephalomyelitis and the outcome for excitatory circuit inputs to individual cortical neurons. Brain, Behavior, and Immunity, 251-260.
    378484091:250Villar-Pazos, S, et al. 2023. Neural deficits in a mouse model of PACS1 syndrome are corrected with PACS1- or HDAC6-targeting therapy. Nature Communications, 6547.
    37591201not listedBoudkkazi, S, et al. 2023. A Noelin-organized extracellular network of proteins required for constitutive and context-dependent anchoring of AMPA-receptors. Neuron, 2544-2556.e9.
    376096301:500Soliño, M, et al. 2023. Large-scale Survey of Excitatory Synapses Reveals Sublamina-specific and Asymmetric Synapse Disassembly in a Neurodegenerative Circuit. iScience, 107262.
    375336531:200Lu, X, et al. 2023. Preserving Extracellular Space for High-quality Optical and Ultrastructural Studies of Whole Mammalian Brains. Cell Reports Methods, 100520.
    373551471:100Yoon, M, et al. 2023. Inhibition of CXXC5 Function Rescues Alzheimer's Disease Phenotypes by Restoring Wnt/β-catenin Signaling Pathway. Pharmacological Research, 106836.
    36732641not listedBalcioglu, A., et al. 2023. Mapping Thalamic Innervation to Individual L2/3 Pyramidal Neurons and Modeling Their 'Readout' of Visual Input. Nature Neuroscience, 470-480.
    364819301:500Burgdorf, J.S., et al. 2022. An IGFBP2-derived Peptide Promotes Neuroplasticity and Rescues Deficits in a Mouse Model of Phelan-McDermid Syndrome. Molecular Psychiatry, .
    358405711:500El Chehadeh, S., et al. 2022. SLITRK2 Variants Associated with Neurodevelopmental Disorders Impair Excitatory Synaptic Function and Cognition in Mice. Nature Communications, 4112.
    357898581:600Katayama, K., et al. 2022. Slitrk2 Deficiency Causes Hyperactivity with Altered Vestibular Function and Serotonergic Dysregulation. iScience, 104604.
    357045701:200Han, Y., et al. 2022. Neuroligin-3 Confines AMPA Receptors into Nanoclusters, Thereby Controlling Synaptic Strength at the Calyx of Held Synapses. Science Advances, eabo4173.
    Immunohistochemistry: Non-Human Primate
    PMID Dilution Publication
    251765251:400Nuhn, J.S., et al. 2014. Developmental localization of adhesion and scaffolding proteins at the cone synapse. Gene expression patterns, 36-50.
    Immunohistochemistry: Rat
    PMID Dilution Publication
    38231472not listedJiang, WR, et al. 2024. A circRNA ceRNA network involved in cognitive dysfunction after chronic cerebral hypoperfusion. Aging, 1161-1181.
    371954491:100Maroto, AF, et al. 2023. The Vestibular Calyceal Junction is Dismantled Following Subchronic Streptomycin in Rats and Sensory Epithelium Stress in Humans. Archives of Toxicology, 1943-1961.
    362296541:150Simonsen, Ø.W., et al. 2022. Retrosplenial and Subicular Inputs Converge on Superficially Projecting Layer V Neurons of Medial Entorhinal Cortex. Brain Structure & Function, 2821-2837.
    347898951:500Pang, K., et al. 2022. An App knock-in rat model for Alzheimer's disease exhibiting Aβ and tau pathologies, neuronal death and cognitive impairments. Cell Research, 157-175.
    34481267not listedMaroto, A.F., et al. 2021. Relationship between vestibular hair cell loss and deficits in two anti-gravity reflexes in the rat. Hearing Research, 108336.
    31604597not listedSchwenk, J., et al. 2019. An ER Assembly Line of AMPA-Receptors Controls Excitatory Neurotransmission and Its Plasticity. Neuron, 680-692.
    296862611:100Hruska, M., et al. 2018. Synaptic nanomodules underlie the organization and plasticity of spine synapses. Nature Neuroscience, 671-682.
    285767291:100Luo, W.W., et al. 2017. Afferent synaptogenesis between ectopic hair-cell-like cells and neurites of spiral ganglion induced by Atoh1 in mammals in vitro. Neuroscience, 185-196.
    282626621:300Zapata, J., et al. 2017. Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission. Nature Communications, 14536.
    280356730.2ug/mlFasoli, A., et al. 2017. Somatic and neuritic spines on tyrosine hydroxylase-immunopositive cells of rat retina. Journal of Comparative Neurology, 1707-1730.
    274656831:250Miller, M.B., et al. 2017. Alternate promoter usage generates two subpopulations of the neuronal RhoGEF Kalirin-7. Journal of Neurochemistry, 889-902.
    Immunoprecipitation: Human
    PMID Dilution Publication
    38452102not listedKaizuka, T, et al. 2024. FAM81A is a postsynaptic protein that regulates the condensation of postsynaptic proteins via liquid-liquid phase separation. PLoS Biology, e3002006.
    Immunoprecipitation: Mouse
    PMID Dilution Publication
    360404820.5mg/mlBarisano, G., et al. 2022. A "Multi-omics" Analysis of Blood-Brain Barrier and Synaptic Dysfunction in APOE4 Mice. The Journal of Experimental Medicine, .
    31235685not listedLuo, P., et al. 2019. Preso regulates NMDA receptor-mediated excitotoxicity via modulating nitric oxide and calcium responses after traumatic brain injury. Cell Death and Disease, 496.
    292942435ugPatel, M.V., et al. 2018. A Novel Short Isoform of Cytosolic PSD-95 Interactor (Cypin) Regulates Neuronal Development. Molecular Neurobiology, 6269-6281.
    2702181910ug/mlVicidomini, C., et al. 2017. Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice. Molecular Psychiatry, 689-702.
    Immunoprecipitation: Rat
    PMID Dilution Publication
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