Our Anti-SAP102 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N19/2. It is KO validated, detects human, mouse, and rat SAP102, and is purified by Protein A chromatography. It is great for use in IHC, ICC.
Synapse-Associated Protein 102, Disks large homolog 3(DLG3) or SAP102 MAGUK scaffold protein is encoded by the gene DLG3. SAP102 is a member of the MAGUK (membrane-associated guanylate kinase) protein family. SAP102 can bind to a number of adhesion molecules and receptors, including NMDA receptors and acts as a scaffold protein to mediate synaptic signaling. This protein plays a role in learning and memory and appears to be required for learning. Mutations in this gene have been associated with X-linked cognitive disability.
Purified by Protein A chromatography
0.5 mg/mL
Monoclonal
N19/2
IgG1
ICC, IHC
Mouse
Dlg3 Dlgh3
105 kDa
Fusion protein amino acids 1-120 of rat SAP102 (accession number Q62936) produced recombinantly in E. Coli
Human, Mouse, Rabbit, Rat
AB_2939255
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.
PBS with 0.09% azide
FL650 Ex: 655 nm, Em: 676 nm
No cross-reactivity against other MAGUK family membersPSD-95, SAP97, Chapsyn-110
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
12 months from date of receipt
Shipped on ice packs
Disks large homolog 3 (PSD-95/SAP90-related protein 1) (Synapse-associated protein 102) (SAP-102) (SAP102)
KO Validated