Anti-SCG10/Stathmin-2 Antibody (L5/1)

7 Citations

Our Anti-SCG10/Stathmin-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone L5/1. It detects human, mouse, and rat SCG10/Stathmin-2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, IP, WB.

Cultured hippocampal neurons (9 DIV) double- Stained for MAP2 (red), L5/1 (green).
Cultured hippocampal neurons (9 DIV) double- Stained for MAP2 (red), L5/1 (green).
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Cultured hippocampal neurons (9 DIV) double- Stained for MAP2 (red), L5/1 (green).
Adult rat neocortex immunohistochemistry.
Adult rat hippocampus immunohistochemistry.

Human, Mouse, Rat
ICC, IHC, IP, WB
Mouse
490
550
594
650
Carrier-Free

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Data Sheet

SKU: 75-063

Volume: 100 µL
Price:
$329.00
Ships: 1-2 business days

Product Details

SCG10/Stathmin-2
Stathmin 2, Superior Cervical Ganglia, Neural Specific 10 (SCG10) is encoded by the gene STMN2 and is a member of the stathmin family of phosphoproteins. Stathmin 2 is involved in regulation of microtubule dynamics and signal transduction. In this manner, Stathmin 2 plays a regulatory role in neuronal growth. Stathmin 2 is expressed in brain in neurons and present in growth cones developing neurons. Diseases associated with STMN2 include down syndrome and Creutzfeldt-jakob disease.
Purified by Protein A chromatography
1 mg/mL
Monoclonal
L5/1
IgG2b
ICC, IHC, IP, WB
Mouse
Stmn2 Scg10 Scgn10
˜20 kDa L5/1 does not work for immunoblotting
Synthetic peptide 155-179 C-terminus of rat SCG10 (ERLQEKERHAAEVRRNKELQVELSG; accession number P21818)
Human, Mouse, Rat
AB_2302747
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.4
WB: 1:250
ICC: 1:500
Unconjugated
No cross-reactivity reported
Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Shipped on ice packs
Stathmin-2 (Superior cervical ganglion-10 protein) (Protein SCG10)
P21818

Product Specific References for Applications and Species

Immunocytochemistry: Rat
PMID Dilution Publication
28521134not listedTortosa, E., et al. 2017. Dynamic palmitoylation targets MAP6 to the axon to promote microtubule stabilization during neuronal polarization. . Neuron, 94(4), pp., 809-825.
214710011:500Levy. A, et al. 2011. Subcellular Golgi localization of stathmin family proteins is promoted by a specific set of DHHC palmitoyl transferases.. Molecular Biology of the Cell, 1930-1942.
Western Blot: Human
PMID Dilution Publication
25032865not listedCarlessi, L., et al. 2014. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency.. Cell Death & Disease, e1342 .
25032865not listedCarlessi, L., et al. 2014. Functional and molecular defects of hiPSC-derived neurons from patients with ATM deficiency.. Cell Death Disease, e1342-e1342.
212157771:250Sobczak, A, et al. 2011. Calmyrin1 binds to SCG10 protein (stathmin2) to modulate neurite outgrowth.. Biochimica et Biophysica Acta, 1025-1037.
Western Blot: Rat
PMID Dilution Publication
24109433not listedVerpelli, C., et al. 2013. Comparative neuronal differentiation of self-renewing neural progenitor cell lines obtained from human induced pluripotent stem cells.. Frontiers in Cellular Neuroscience, not listed.
21368059not listedDeWald, L, et al. 2011. The RE1 binding protein REST regulates oligodendrocyte differentiation.. Journal of Neuroscience, 3470-3483.

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