Anti-Slo2.2/Slack K+ Channel Antibody FL490 Conjugate (N3/26)

Name: Anti-Slo2.2/Slack K+ Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-051-FL490
Price: 515.0 USD
Availability: InStock

Our Anti-Slo2.2/Slack K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N3/26. It is KO validated, detects human, marine mollusk, mouse, and rat Slo2.2/Slack K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Human, Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

KO Validated

SKU: 75-051-FL490

Volume: 200 µL

Variant

Price:

$515.00

Quantity:

Product Details

Target

Slo2.2/Slack K+ channel

Target Description

Potassium channel subfamily T member 1 or -KCNT1/Slo2.2/Slack K+ channel is encoded by the gene KCNT1. Slo2.2 is a member of the the voltage-gated ion channel (vic) superfamily, and the KCNT protein family, which is made of KCNT1 and KCNT2. Slo2.2 functions as an outwardly rectifying potassium channel subunit to contribute to ion conductance and signaling pathways. Slo2.2 can be activated by high intracellular sodium or chloride levels. Slo2.2 is expressed at the membrane in many areas of the brain, brainstem, spinal cord, spleen and liver. Mutations in this gene cause the early-onset epileptic disorders

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N3/26

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnt1 Slack

Molecular Weight

140 kDa

Antigen

Fusion protein amino acids 1168-1237 of rat Slo2.2 (accession number NP_068625) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2939224

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Potassium channel subfamily T member 1 (Sequence like a calcium-activated potassium channel subunit)

UniProt Details

UniProt (Human): Q5JUK3
UniProt (Immunogen Species): Q9Z258

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Anti-Slo2.2/Slack K+ Channel Antibody FL490 Conjugate (N3/26)

SKU: 75-051-FL490

Product Details

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