Anti-THAP1 Antibody (N325B/65)

Name: Anti-THAP1 Antibody
Brand: NeuroMab
SKU: 75-310
Price: 319.0 USD
Availability: InStock

Our Anti-THAP1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N325B/65. It detects human THAP1, and is purified by Protein A chromatography. It is great for use in ICC, WB.

Transfected cell immunoblot: extracts of COS cells transiently transfected with V5/His-tagged THAP1 or untagged Kv2.1 plasmid and probed with N325B/65 TC supe (left) and mouse anti-V5 (right).

Species Reactivity

Human

Applications

ICC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-310

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

THAP1

Target Description

THAP (Thanatos-associated protein) domain-containing, apoptosis-associated protein 1)domain-containing protein 1, Nuclear Proapoptotic Factor or Dystonia 6, Torsion (Autosomal Dominant) is encoded by the gene THAP1. THAP1 is a DNA-binding transcription regulator involved in endothelial cell proliferation, G1/S cell-cycle progression and is thought to play a role in apoptosis. Thap1 is expressed in many tissues including heart, skeletal muscle, kidney, liver, brain and placenta. Diseases associated with this gene include Dystonia.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N325B/65

Isotype

IgG3

Applications

ICC, WB

Host Species

Mouse

Gene Name

THAP1

Molecular Weight

30 kDa

Antigen

Fusion protein amino acids 1-213 (full-length) of human THAP1 (accession number Q9NVV9) produced recombinantly in E. Coli

Species Reactivity

Human

Antibody Registry ID

AB_2315944

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

THAP domain-containing protein 1

UniProt Details

UniProt (Human): Q9NVV9
UniProt (Immunogen Species): Q9NVV9

Product Specific References for Applications and Species

Western Blot: Human | Mouse

Western Blot: Human
PMID	Dilution	Publication
25231164	1:5 (supe)	Ortiz-Virumbrales, M., et al. 2014. Dystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractions. Acta Neuropathology Communications, 139.

Western Blot: Mouse
PMID	Dilution	Publication
25231164	1:5 (supe)	Ortiz-Virumbrales, M., et al. 2014. Dystonia type 6 gene product Thap1: identification of a 50 kDa DNA-binding species in neuronal nuclear fractions. Acta Neuropathology Communications, 139.

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Anti-THAP1 Antibody (N325B/65)

SKU: 75-310

Product Details

Product Specific References for Applications and Species

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