Anti-THIK-2 K+ Channel Antibody FL490 Conjugate (N468/37)

Name: Anti-THIK-2 K+ Channel Antibody FL490 Conjugate
Brand: NeuroMab
SKU: 75-462-FL490
Price: 460.0 USD
Availability: InStock

Our Anti-THIK-2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N468/37. It detects mouse and rat THIK-2, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

550

594

650

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Data Sheet

SKU: 75-462-FL490

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

THIK-2

Target Description

Potassium two pore domain channel subfamily K member 12 is encoded by the gene KCNK12. KCNK12 is a member of the two pore domain potassium channel (TC 1.A.1.8) family. KCNK12 has not been shown to be a functional channel; however, it may require other non-pore-forming proteins for activity. KCNK12 is highly expressed in the brain. Diseases associated with KCNK12 include Skin Angiosarcoma and Birk-Barel Syndrome.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N468/37

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Kcnk12 mntk1

Molecular Weight

47 kDa

Antigen

Fusion protein amino acids 313-408 (cytoplasmic C-terminus) of mouse THIK-2 (accession number Q76M80) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940540

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL490 Ex: 491 nm, Em: 515 nm

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

THIK-2 (Potassium channel subfamily K member 12) (Tandem pore domain halothane-inhibitedpotassium channel 2) (Kcnk12) (MNTK1)

UniProt Details

UniProt (Human): Q9HB15
UniProt (Immunogen Species): Q76M80

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Anti-THIK-2 K+ Channel Antibody FL490 Conjugate (N468/37)

SKU: 75-462-FL490

Product Details

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