Anti-Thorase/Atad1 Antibody (N125/10)
Our Anti-Thorase/Atad1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N125/10. It is KO validated, detects human, mouse, and rat Thorase/Atad1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
![Immunoblots on membranes prepared from whole mouse (MBM) and rat (RBM) brain, and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)], and cerebellum [HBM(Cb)].](http://www.antibodiesinc.com/cdn/shop/products/validation-image-73-157-n125-10-wb3_{width}x.jpg?v=1626903644)
Adult rat hippocampus immunohistochemistry.
![Immunoblots on membranes prepared from whole mouse (MBM) and rat (RBM) brain, and from human hippocampus [HBM(H)], cerebral cortex [HBM(Cx)], and cerebellum [HBM(Cb)].](http://www.antibodiesinc.com/cdn/shop/products/validation-image-73-157-n125-10-wb3_1024x.jpg?v=1626903644)
Product Specific References for Applications and Species
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 35550246 | not listed | Wang, L., et al. 2022. Conserved structural elements specialize ATAD1 as a membrane protein extraction machine. Elife, e73941. |
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 34284000 | not listed | González-Martín, A., et al. 2021. c-Abl regulates a synaptic plasticity-related transcriptional program involved in memory and learning. Progress in Neurobiology, 102122. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 36409067 | 1:1000 | Winter, J.M., et al. 2022. Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction. Elife, e82860. |
| 34351705 | not listed | Nuebel, E., et al. 2021. The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder. EMBO Reports, e51991. |
| 29390050 | not listed | Piard, J., et al. 2018. A homozygous ATAD1 mutation impairs postsynaptic AMPA receptor trafficking and causes a lethal encephalopathy. Brain, 651-661. |
| 28180185 | 1:100 | Ahrens-Nicklas, R.C., et al. 2017. Precision therapy for a new disorder of AMPA receptor recycling due to mutations in ATAD1. Neurology. Genetics, e130. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 34767452 | not listed | Antico, O., et al. 2021. Global ubiquitylation analysis of mitochondria in primary neurons identifies endogenous Parkin targets following activation of PINK1. Science Advances, eabj0722. |
| 34284000 | not listed | González-Martín, A., et al. 2021. c-Abl regulates a synaptic plasticity-related transcriptional program involved in memory and learning. Progress in Neurobiology, 102122. |
| 33147468 | not listed | George, K.E., et al. 2020. AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF. Cell Reports, 108329. |
| 29237760 | not listed | Umanah, G.K., et al. 2017. Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel. Science Translational Medicine, eaah4985. |
| 28180185 | 1:100 | Ahrens-Nicklas, R.C., et al. 2017. Precision therapy for a new disorder of AMPA receptor recycling due to mutations in ATAD1. Neurology. Genetics, e130. |
| 24843043 | not listed | Chen, Y.C., et al. 2014. Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins.. The EMBO Journal, 1548-1564. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 25253868 | 1:1000 | Prendergast, J., et al. 2014. Ganglioside regulation of AMPA receptor trafficking.. Journal of Neuroscience, 13246-13258. |