Anti-VAChT Antibody FL550 Conjugate (N425/45)

Name: Anti-VAChT Antibody FL550 Conjugate
Brand: NeuroMab
SKU: 75-429-FL550
Price: 460.0 USD
Availability: InStock

Our Anti-VAChT mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N425/45. It detects mouse and rat VAChT, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

Unconjugated

490

594

650

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Data Sheet

SKU: 75-429-FL550

Volume: 200 µL

Variant

Price:

$460.00

Quantity:

Product Details

Target

VAChT

Target Description

Vesicular acetylcholine transporter (VaCht), or Solute Carrier Family 18 Member A3 is encoded by the gene Slc18a3 and is a member of the vesicular amine transporter family. VaCht transports acetylcholine into secretory vesicles for release into the extracellular space. VaCht is expressed in major cholinergic cell groups in the peripheral and central cholinergic nervous systems. Diseases associated with SLC18A3 include Myasthenic Syndrome and Presynaptic and Presynaptic Congenital Myasthenic Syndromes.

Format

Purified by Protein A chromatography

Concentration

0.5 mg/mL

Clonality

Monoclonal

Clone

N425/45

Isotype

IgG1

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Slc18a3 Vacht Vat

Molecular Weight

60 kDa

Antigen

Fusion protein amino acids 55-125 (first vesicle lumen domain) of rat VAChT (accession number Q62666) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2940425

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography and conjugation of purified mAb. Purified mAbs are >90% specific antibody.

Buffer

PBS with 0.09% azide

Conjugate

FL550 Ex: 550 nm, Em: 575 nm

Specificity

Does not cross-react with VMAT1 or VMAT2

Quality Control

Each new lot of antibody is quality control tested by IHC on either rat or mouse brain and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

12 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Vesicular acetylcholine transporter (VAChT) (rVAT) (Solute carrier family 18 member 3)

UniProt Details

UniProt (Human): Q16572
UniProt (Immunogen Species): Q62666

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Anti-VAChT Antibody FL550 Conjugate (N425/45)

SKU: 75-429-FL550

Product Details

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