Anti-VDAC1 Antibody (N152B/23)

23 Citations

Our Anti-VDAC1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N152B/23. It is KO validated, detects human, mouse, and rat VDAC1, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Immunoblot against membranes from livers of wild-type (WT) and VDAC1 knockout (KO) mice and brains of WT mice (MBM) and rat (RBM). Liver samples courtesy of Tatiana Sheiko and Bill Craigen (Baylor College of Medicine).
Array tomography immunofluorescence of 70 nm sections of LRWhite-embedded adult mouse hippocampus. Two consecutive sections labeled with N152B/23 (bottom) and DAPI (top), where low level autofluorescence reveals mitochondria appearing as brighter elongated structures within darker apical dendrites (arrows). Images courtesy of Kristina Micheva (Stanford).
Adult rat hippocampus immunohistochemistry.
Western blot for mitochondrial Ca 2+ uptake proteins in hippocampus,cortex and cerebellum lysates from 6 month old contol mice (Control) and mice with haploinsufficiency of the mitochondrial Ca2+ uniporter (MCU+/−). Image from publication CC-BY-4.0. PMID:36274588
Immunoblot against membranes from livers of wild-type (WT) and VDAC1 knockout (KO) mice and brains of WT mice (MBM) and rat (RBM). Liver samples courtesy of Tatiana Sheiko and Bill Craigen (Baylor College of Medicine).
Immunoblot against membranes from livers of wild-type (WT) and VDAC1 knockout (KO) mice and brains of WT mice (MBM) and rat (RBM). Liver samples courtesy of Tatiana Sheiko and Bill Craigen (Baylor College of Medicine).
Array tomography immunofluorescence of 70 nm sections of LRWhite-embedded adult mouse hippocampus. Two consecutive sections labeled with N152B/23 (bottom) and DAPI (top), where low level autofluorescence reveals mitochondria appearing as brighter elongated structures within darker apical dendrites (arrows). Images courtesy of Kristina Micheva (Stanford).
Adult rat hippocampus immunohistochemistry.
Western blot for mitochondrial Ca 2+ uptake proteins in hippocampus,cortex and cerebellum lysates from 6 month old contol mice (Control) and mice with haploinsufficiency of the mitochondrial Ca2+ uniporter (MCU+/−). Image from publication CC-BY-4.0. PMID:36274588

Human, Mouse, Rat
ICC, IHC, WB
Mouse
490
550
594
650

Go to Full Product Details

Data Sheet
KO Validated KO Validated

SKU: 75-204

Volume: 100 µL
1-2 business days
Price:
$319.00

Product Specific References for Applications and Species

Immunocytochemistry: Human
PMID Dilution Publication
350648711:500Fularczyk, N., et al. 2022. A Learning Based Framework for Disease Prediction from Images of Human-Derived Pluripotent Stem Cells of Schizophrenia Patients.. Neuroinformatics, .
Immunohistochemistry: Mouse
PMID Dilution Publication
258340541:50Joshi, D.C., et al. 2015. Deletion of mitochondrial anchoring protects dysmyelinating shiverer: implications for progressive MS.. Journal of Neuroscience, 5293-306.
Western Blot: Human
PMID Dilution Publication
32042150not listedNaseri, N.N., et al. 2020. Aggregation of mutant cysteine string protein-α via Fe-S cluster binding is mitigated by iron chelators.. Nature structural and molecular biology, 192-201.
28945249not listedGersch, M., et al. 2017. Mechanism and regulation of the Lys6-selective deubiquitinase USP30. . Nature structural & molecular biology, 920-930.
235607501:100,000Davies, P., et al. 2013. Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies.. Biochemical Journal, 101-13.
Western Blot: Mouse
PMID Dilution Publication
37883842not listedPiroli, GG, et al. 2023. Defective function of α-ketoglutarate dehydrogenase exacerbates mitochondrial ATP deficits during complex I deficiency. Redox Biology, 102932.
362745881:1000Devine, M.J., et al. 2022. Mitochondrial Ca2+ Uniporter Haploinsufficiency Enhances Long-Term Potentiation at Hippocampal Mossy Fibre Synapses. Journal of Cell Science, .
35417693not listedCarnazza, K.E., et al. 2022. Synaptic vesicle binding of α-synuclein is modulated by β-and γ-synucleins. . Cell Reports, 110675.
35269919not listedZhai, R., et al. 2022. Myocardial GRK2 Reduces Fatty Acid Metabolism and β-Adrenergic Receptor-Mediated Mitochondrial Responses.. International journal of molecular sciences, 2777.
352635921:1000Sayles, N.M., et al. 2022. Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy.. Cell reports, 110475.
341526081:1000López‐Doménech, G., et al. 2021. Loss of neuronal Miro1 disrupts mitophagy and induces hyperactivation of the integrated stress response. . The EMBO journal, e100715.
30538174not listedSato, P.Y., et al. 2018. Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation.. Science Signalling, eaau0144.
299497561:4000Stein, C.S., et al. 2018. Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency.. Cell reports, 3710-3720.e8.
27413152not listedVolpicelli-Daley, L.A., et al. 2016. G2019S-LRRK2 Expression Augments α-Synuclein Sequestration into Inclusions in Neurons.. Journal of Neuroscience, 7415-27.
26777142not listedPonnalagu, D., et al. 2016. Molecular identity of cardiac mitochondrial chloride intracellular channel proteins.. Mitochondrion, 6-14.
26450614not listedPiroli, G.G., et al. 2016. Succination is Increased on Select Proteins in the Brainstem of the NADH dehydrogenase (ubiquinone) Fe-S protein 4 (Ndufs4) Knockout Mouse, a Model of Leigh Syndrome.. Molecular & Cellular Proteomics, 445-61.
242700801:80,000Simeone, K.A., et al. 2014. Targeting deficiencies in mitochondrial respiratory complex I and functional uncoupling exerts anti-seizure effects in a genetic model of temporal lobe epilepsy and in a model of acute temporal lobe seizures.. Experimental Neurology, 84-90.
235607501:100,000Davies, P., et al. 2013. Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies.. Biochemical Journal, 101-13.
23467820not listedChen, M., et al. 2013. Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting.. Circulation Research, 1121-34.
Western Blot: Rat
PMID Dilution Publication
317406741:1000Li, J., et al. 2019. Mitochondrial deficits in human iPSC-derived neurons from patients with 22q11. 2 deletion syndrome and schizophrenia. . Translational psychiatry, 1-10.
26777142not listedPonnalagu, D., et al. 2016. Molecular identity of cardiac mitochondrial chloride intracellular channel proteins.. Mitochondrion, 6-14.
267184751:5 (TC supe)Testai, L., et al. 2016. Expression and function of Kv7.4 channels in rat cardiac mitochondria: possible targets for cardioprotection.. Cardiovascular Research, 40-50.

Bulk Order Anti-VDAC1 Antibody

Related Products

Recently Viewed