Anti-Cav1.2 Ca2+ Channel Antibody (N263/31)

Our Anti-Cav1.2 Ca2+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N263/31. It detects human, mouse, and rat Cav1.2 Ca2+ channel, and is purified by Protein A chromatography. It is great for use in ICC, WB.



SKU: 75-257

Volume: 100 µL
1-2 business days
Price:
Sale price$319.00

Product Specific References for Applications and Species

Fluorescence Resonance Energy Transfer: Rat
PMID Dilution Publication
270766161:100Bannister, J.P., et al. 2016. Rab25 influences functional Cav1.2 channel surface expression in arterial smooth muscle cells. American Journal of Physiology. Cell Physiology, C885-C895.
Immunocytochemistry: Guinea Pig
PMID Dilution Publication
314034021:200Morgenstern, T.J., et al. 2019. A potent voltage-gated calcium channel inhibitor engineered from a nanobody targeted to auxiliary CaVβ subunits. Elife, e49253.
Immunocytochemistry: Mouse
PMID Dilution Publication
377027871:100Akin, EJ, et al. 2023. ANO1, CaV1.2, and IP3R form a localized unit of EC-coupling in mouse pulmonary arterial smooth muscle. The Journal of General Physiology, 0.
374384791:100Cserne Szappanos, H., et al. 2023. Cytoskeletal Disarray Increases Arrhythmogenic Vulnerability During Sympathetic Stimulation in a Model of Hypertrophic Cardiomyopathy. Scientific Reports, 11296.
347502631:5 (supe)Vierra, N.C., et al. 2021. Regulation of neuronal excitation-transcription coupling by Kv2.1-induced clustering of somatic L-type Ca2+ channels at ER-PM junctions. PNAS: USA, .
3308233910ug/mlPrada, M.P., et al. 2020. AKAP5 complex facilitates purinergic modulation of vascular L-type Ca2+ channel CaV1.2. Nature Communications, 5303.
316638501:5 (supe)Vierra, N.C., et al. 2019. Kv2. 1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons. Elife, e49953.
Immunocytochemistry: Rat
PMID Dilution Publication
344319811:100Isensee, J., et al. 2021. Depolarization induces nociceptor sensitization by CaV1.2-mediated PKA-II activation. Journal of Cell Biology, .
27364017not listedEichel, C.A., et al. 2016. Lateral Membrane-Specific MAGUK CASK Down-Regulates NaV1.5 Channel in Cardiac Myocytes. Circulation Research, 544-56.
Immunohistochemistry: Human
PMID Dilution Publication
281194641:1000Nystoriak, M.A., et al. 2017. Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes. Scientific Signaling, eaaf9647.
Immunohistochemistry: Mouse
PMID Dilution Publication
375073755ug/mlCasas, M., et al. 2023. NPC1-dependent alterations in KV2.1–CaV1.2 nanodomains drive neuronal death in models of Niemann-Pick Type C disease. Nature Communications, 4553.
347502631:5 (supe)Vierra, N.C., et al. 2021. Regulation of neuronal excitation-transcription coupling by Kv2.1-induced clustering of somatic L-type Ca2+ channels at ER-PM junctions. PNAS: USA, .
Immunoprecipitation: Rat
PMID Dilution Publication
246813471:500Liu, W., et al. 2014. KCNE2 modulates cardiac L-type Ca(2+) channel.. Journal of Molecular Cellular Cardiology, 208-218.
PLA: Human
PMID Dilution Publication
281194641:1000Nystoriak, M.A., et al. 2017. Ser1928 phosphorylation by PKA stimulates the L-type Ca2+ channel CaV1.2 and vasoconstriction during acute hyperglycemia and diabetes. Scientific Signaling, eaaf9647.
PLA: Mouse
PMID Dilution Publication
38860414not listedXu, B, et al. 2024. Differential Downregulation of β1-Adrenergic Receptor Signaling in the Heart. Journal of the American Heart Association, e033733.
STED: Rabbit
PMID Dilution Publication
29549309not listedZhang, X.D., et al. 2018. Coupling of SK channels, L-type Ca2+ channels, and ryanodine receptors in cardiomyocytes. Scientific Reports, 4670.
Western Blot: Guinea Pig
PMID Dilution Publication
267644821:500Nassal, D.M., et al. 2016. Myocardial KChIP2 expression in guinea pig resolves an expanded electrophysiologic role. PLoS One, e0146561.
Western Blot: Human
PMID Dilution Publication
244016931:200Duan, L., et al. 2014. Stem cell derived basal forebrain cholinergic neurons from Alzheimer''s disease patients are more susceptible to cell death.. Molecular Neurdegeneration, 3.
238580111:250Narayanan, D., et al. 2013. Smooth muscle cell transient receptor potential polycystin-2 (TRPP2) channels contribute to the myogenic response in cerebral arteries.. Journal of Physiology, 5031-5046.
Western Blot: Mouse
PMID Dilution Publication
32442021not listedGupte, R., et al. 2020. Glucose-6-phosphate dehydrogenase increases Ca2+ currents by interacting with Cav1.2 and reducing intrinsic inactivation of the L-type calcium channel. American Journal of Physiology. Heart and Circulatory Physiology, H144-H158.
Western Blot: Rat
PMID Dilution Publication
334532401:1000Nasu, F., et al. 2021. Azelnidipine treatment reduces the expression of Cav1.2 protein. Life Sciences, 119043.
31337710not listedJiang, M., et al. 2019. S-Palmitoylation of junctophilin-2 is critical for its role in tethering the sarcoplasmic reticulum to the plasma membrane. Journal of Biological Chemistry, 13487-13501.
256103721:1000Perissinotti, P.P., et al. 2015. Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice.. Frontiers in Cellular Neuroscience, 444.
247039041:1000Perissinotti, P.P., et al. 2014. Down-regulation of endogenous KLHL1 decreases voltage-gated calcium current density.. Cell Calcium, 269-280.
238580111:250Narayanan, D., et al. 2013. Smooth muscle cell transient receptor potential polycystin-2 (TRPP2) channels contribute to the myogenic response in cerebral arteries.. Journal of Physiology, 5031-5046.
23568894not listedBannister, J.P., et al. 2013. The voltage-dependent L-type Ca2+ (CaV1.2) channel C-terminus fragment is a bi-modal vasodilator. Journal of Physiology, 2987-2998.

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