Anti-FGF13/FHF2 Antibody (N91/27)

Name: Anti-FGF13/FHF2 Antibody
Brand: NeuroMab
SKU: 75-134
Price: 319.0 USD
Availability: InStock

Our Anti-FGF13/FHF2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N91/27. It detects human and mouse FGF13/FHF2, and is purified by Protein A chromatography. It is great for use in ICC, IP, WB.

Transfected cell immunoblot: extracts of whole rat brain homogenate (WBH) and COS cells transfected with GFP-tagged FGF11/FHF3 and FGF13/FHF2 and untagged Kv2.1 plasmids and probed with N91/27 (left) and N52A/42 (right) TC supe.

Species Reactivity

Human, Mouse

Applications

ICC, IP, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-134

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

FGF13/FHF2

Target Description

Fibroblast growth factor 13, FHF2 or FGF13 is encoded by the gene FGF13. FHF2 is a member of the fibroblast growth factor homologous factors family (a subfamily of fibroblast growth factors.). FHFs have a role in regulation of voltage fated sodium channels (Nav channels) and are thought to be involved in nervous system development. FGF13 is expressed in the nervous system and other tissues. Diseases associated with FGF13 include X-Linked Congenital Generalized Hypertrichosis and Wildervanck Syndrome.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N91/27

Isotype

IgG1

Applications

ICC, IP, WB

Host Species

Mouse

Gene Name

FGF13 FHF2

Molecular Weight

28 kDa

Antigen

Fusion protein amino acids 53-245 of human FGF13a (accession number Q92913) produced recombinantly in E. Coli

Species Reactivity

Human, Mouse

Antibody Registry ID

AB_2104047

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.60

Dilution Ranges

WB: 1:500

Conjugate

Unconjugated

Specificity

Cross-reacts with FGF13a and FGF13bDoes not cross-react with FGF11, FGF12 or FGF14 expressed in heterologous cells

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Fibroblast growth factor 13 (FGF-13) (Fibroblast growth factor homologous factor 2) (FHF-2)

UniProt Details

UniProt (Human): Q92913
UniProt (Immunogen Species): Q92913

Product Specific References for Applications and Species

Western Blot: Mouse

Western Blot: Mouse
PMID	Dilution	Publication
37516919	1:300	Lesage, A, et al. 2023. Determinants of iFGF13-mediated Regulation of Myocardial Voltage-gated Sodium (NaV) Channels in Mouse. The Journal of general physiology, 0.

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Anti-FGF13/FHF2 Antibody (N91/27)

SKU: 75-134

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-FGF13/FHF2 Antibody

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