Anti-KChIP2b K+ Channel Antibody (K60/73)
Our Anti-KChIP2b K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone K60/73. It detects canine, human, mouse, pig, and rat KChIP2b K+ channel, and is purified by Protein A chromatography. It is great for use in CHiP, IHC, ICC, IP, WB.
Adult rat hippocampus immunohistochemistry.
Product Specific References for Applications and Species
- ChIP: Mouse
- Immunocytochemistry: Human | Mouse | Rat
- Immunohistochemistry: Mouse | Rat
- Immunoprecipitation: Human
- Western Blot: Canine | Human | Mouse | Rabbit | Rat | Swine
- Additional Publications: Unspecified
| Chromatin Immunoprecipitation: Mouse | ||
| PMID | Dilution | Publication |
| 31017573 | 1:50 | Carrillo-Reid, L., et al. 2019. Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons. . Elife, e40818. |
| 27349185 | 13 ug/ml | Winther, S.V., et al. 2016. Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling. . Scientific Reports, 1-12. |
| Immunocytochemistry: Human | ||
| PMID | Dilution | Publication |
| 27349185 | 10.4 ug/ml | Winther, S.V., et al. 2016. Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling. . Scientific Reports, 1-12. |
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 21507952 | 1:10 (supe) | Cheng, L., et al. 2011. Cortactin is required for N-cadherin regulation of Kv1.5 channel function.. The Journal of Biological Chemistry, 20478-20489. |
| Immunocytochemistry: Rat | ||
| PMID | Dilution | Publication |
| 28263709 | 1:50 | Nassal, D.M., et al. 2017. KChIP2 is a core transcriptional regulator of cardiac excitability. . Elife, 17304. |
| 25551770 | 1:500 | Isensee, J., et al. 2014. Subgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit.. PLoS One, e115731. |
| 22612322 | 1:500 | Pruunsild, P., et al. 2012. Subcellular localization and transcription regulatory potency of KCNIP/Calsenilin/DREAM/KChIP proteins in cultured primary cortical neurons do not provide support for their role in CRE-dependent gene expression.. Journal of Neurochemistry, 29-43. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 36097791 | 1:50 | Chiu, C.Y., et al. 2022. K+ Channel Kv4.1 is Expressed in the Nociceptors/Secondary Nociceptive Neurons and Participates in Pain Regulation. European Journal of Pain, 2238-2256. |
| 22612819 | not listed | Menegola, M., et al. 2012. The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice.. Epilepsia, 142-149. |
| 22612819 | not listed | Menegola, M., et al. 2012. The importance of immunohistochemical analyses in evaluating the phenotype of Kv channel knockout mice.. Epilepsia, 142-149. |
| 17122038 | not listed | Menegola, M. , et al. 2006. Unanticipated region- and cell-specific downregulation of individual KChIP auxiliary subunit isotypes in Kv4.2 knock-out mouse brain.. Journal of Neuroscience, 2137-42. |
| Immunohistochemistry: Rat | ||
| PMID | Dilution | Publication |
| 28330877 | 1:50 | Kuo, Y.L., et al. 2017. K + Channel Modulatory Subunits KChIP and DPP Participate in Kv4-Mediated Mechanical Pain Control.. Journal of Neuroscience, 4391-4404. |
| 24037673 | not listed | Rainnie, D.G., et al. 2014. Distribution and functional expression of Kv4 family α subunits and associated KChIP β subunits in the bed nucleus of the stria terminalis.. Journal of Comparative Neurology, 609-25. |
| 18727953 | not listed | Monaghan, M.M., et al. 2008. Altered expression and localization of hippocampal A-type potassium channel subunits in the pilocarpine-induced model of temporal lobe epilepsy.. Neuroscience, 550-562. |
| Immunoprecipitation: Human | ||
| PMID | Dilution | Publication |
| 20498229 | not listed | Levy, D.I., et al. 2010. The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.. The Journal of Physiology, 2657-2668. |
| Western Blot: Canine | ||
| PMID | Dilution | Publication |
| 22820054 | not listed | Özgen, N., et al. 2012. Microtubules and angiotensin II receptors contribute to modulation of repolarization induced by ventricular pacing.. Heart Rhythm, 1865-1872. |
| 19632239 | 1:200 | Calloe, K., et al. 2010. Differential effects of the transient outward K(+) current activator NS5806 in the canine left ventricle.. Journal of Molecular and Cellular Cardiology, 191-200. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 20709747 | not listed | Foeger, N.C., et al. 2010. Co-assembly of Kv4 {alpha} subunits with K+ channel-interacting protein 2 stabilizes protein expression and promotes surface retention of channel complexes.. The Journal of Biological Chemistry, 33413-33422. |
| 20498229 | not listed | Levy, D.I., et al. 2010. The membrane protein MiRP3 regulates Kv4.2 channels in a KChIP-dependent manner.. The Journal of Physiology, 2657-2668. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 32822706 | not listed | Tiwari, D., et al. 2020. The potassium channel Kv4. 2 regulates dendritic spine morphology, electroencephalographic characteristics and seizure susceptibility in mice. . Experimental Neurology, 113437. |
| 31071333 | not listed | Ednie, A.R., et al. 2019. Reduced hybrid/complex N-glycosylation disrupts cardiac electrical signaling and calcium handling in a model of dilated cardiomyopathy.. Journal of Molecular and Cellular Cardiology, 13-23. |
| 31017573 | 1:1000 | Carrillo-Reid, L., et al. 2019. Mutant huntingtin enhances activation of dendritic Kv4 K+ channels in striatal spiny projection neurons. . Elife, e40818. |
| 27697822 | not listed | Khandekar, A., et al. 2016. Notch-mediated epigenetic regulation of voltage-gated potassium currents. . Circulation Research, 1324-1338. |
| 27349185 | 3.47 ug/ml | Winther, S.V., et al. 2016. Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling. . Scientific Reports, 1-12. |
| 26611208 | not listed | Zhang, X., et al. 2016. Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias.. Basic Research in Cardiology, 1-16. |
| 26297229 | 1:1000 | Liu, W.J., et al. 2015. Manipulation of KCNE2 expression modulates action potential duration and Ito and IK in rat and mouse ventricular myocytes.. American Journal of Physiology-Heart and Circulatory Physiology, H1288-H1302. |
| 24375641 | 1:200 | Lopez-Izquierdo, A., et al. 2014. The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization.. American Journal of Physiology-Heart and Circulatory Physiology, H747-H754. |
| 24225951 | not listed | Mercer, R.C., et al. 2013. The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6.. The Journal of Biological Chemistry, 37241-37255. |
| 24099801 | 3.5ug/ml | Speerschneider, T., et al. 2013. Development of heart failure is independent of K+ channel-interacting protein 2 expression.. The Journal of Physiology, 5923-5937. |
| 23713033 | not listed | Foeger, N.C., et al. 2013. Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents.. The Journal of Physiology, 4149-4166. |
| 22539834 | not listed | Marionneau, C., et al. 2012. The sodium channel accessory subunit Navβ1 regulates neuronal excitability through modulation of repolarizing voltage-gated K⁺ channels.. Journal of Neuroscience, 5716-5727. |
| 22514734 | not listed | Suzuki, T., et al. 2012. Multistep ion channel remodeling and lethal arrhythmia precede heart failure in a mouse model of inherited dilated cardiomyopathy.. PLoS One, e35353. |
| 21943606 | 1:500 | Sun, W., et al. 2011. DPP6 establishes the A-type K(+) current gradient critical for the regulation of dendritic excitability in CA1 hippocampal neurons.. Neuron, 1102-15. |
| 21646717 | not listed | Stein, A.B., et al. 2011. Loss of H3K4 methylation destabilizes gene expression patterns and physiological functions in adult murine cardiomyocytes.. Journal of Clinical Investigation, 2641-2650. |
| 21507952 | not listed | Cheng, L., et al. 2011. Cortactin is required for N-cadherin regulation of Kv1.5 channel function.. The Journal of Biological Chemistry, 20478-20489. |
| 20974681 | not listed | Yang, K.C., et al. 2010. Homeostatic regulation of electrical excitability in physiological cardiac hypertrophy.. The Journal of Physiology, 5015-5032. |
| 20943905 | not listed | Norris, A.J., et al. 2010. Interdependent roles for accessory KChIP2, KChIP3, and KChIP4 subunits in the generation of Kv4-encoded IA channels in cortical pyramidal neurons.. Journal of Neuroscience, 13644-13655. |
| 19223600 | 1:1000 | Alexander, J.C., et al. 2009. The role of calsenilin/DREAM/KChIP3 in contextual fear conditioning.. Learning & Memory, 167-77. |
| 19223600 | 1:1000 | Alexander, J.C., et al. 2009. The role of calsenilin/DREAM/KChIP3 in contextual fear conditioning.. Learning & Memory, 167-77. |
| 18482733 | not listed | Marionneau, C., et al. 2008. PPARalpha-mediated remodeling of repolarizing voltage-gated K+ (Kv) channels in a mouse model of metabolic cardiomyopathy.. Journal of Molecular and Cellular Cardiology, 1002-1015. |
| 18451341 | not listed | Marionneau, C., et al. 2008. Distinct cellular and molecular mechanisms underlie functional remodeling of repolarizing K+ currents with left ventricular hypertrophy.. Circulation Research, 1406-1415. |
| 18045613 | not listed | Niwa, N., et al. 2008. Kv4.3 is not required for the generation of functional Ito,f channels in adult mouse ventricles.. Journal of Molecular and Cellular Cardiology, 95-104. |
| Western Blot: Rabbit | ||
| PMID | Dilution | Publication |
| 20405051 | not listed | Xu, X., et al. 2010. Long-term fish oil supplementation induces cardiac electrical remodeling by changing channel protein expression in the rabbit model.. PLoS One, e10140. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 28330877 | 1:400 | Kuo, Y.L., et al. 2017. K + Channel Modulatory Subunits KChIP and DPP Participate in Kv4-Mediated Mechanical Pain Control.. Journal of Neuroscience, 4391-4404. |
| 28263709 | 1:50 | Nassal, D.M., et al. 2017. KChIP2 is a core transcriptional regulator of cardiac excitability. . Elife, 17304. |
| 27259067 | 1:1000 | Lei, Z., et al. 2016. Reduced expression of IA channels is associated with post-ischemic seizures. . Epilepsy Research, 40-48. |
| 26297229 | 1:1000 | Liu, W.J., et al. 2015. Manipulation of KCNE2 expression modulates action potential duration and Ito and IK in rat and mouse ventricular myocytes.. American Journal of Physiology-Heart and Circulatory Physiology, H1288-H1302. |
| 26016905 | 1:2000 | You, T., et al. 2015. Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function.. International Journal of Molecular Medicine, 309-315. |
| 22367544 | not listed | Jeyaraj, D., et al. 2012. Circadian rhythms govern cardiac repolarization and arrhythmogenesis.. Nature, 96-99. |
| 20849929 | 1:1000 | Dabrowska, J. , et al. 2010. Expression and distribution of Kv4 potassium channel subunits and potassium channel interacting proteins in subpopulations of interneurons in the basolateral amygdala.. Neuroscience, 721-33. |
| 19372218 | not listed | Jiang, M., et al. 2009. Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2.. The Journal of Biological Chemistry, 16452-16462. |
| Western Blot: Swine | ||
| PMID | Dilution | Publication |
| 24376615 | not listed | Kant, R., et al. 2013. NHE isoform switching and KChIP2 upregulation in aging porcine atria.. PLoS One, e82951. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 26239200 | Cheng, C.F., et al. 2016. Coexpression of auxiliary subunits KChIP and DPPL in potassium channel Kv4-positive nociceptors and pain-modulating spinal interneurons.. Journal of Comparative Neurology, 846-873. | |
| 26205295 | El Gebeily, G., et al. 2015. Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart.. Journal of Molecular and Cellular Cardiology, 85-94. | |
| 24793047 | Rudakova, E., et al. 2015. Localization of Kv4.2 and KChIP2 in lipid rafts and modulation of outward K+ currents by membrane cholesterol content in rat left ventricular myocytes.. Pflügers Archiv: European Journal of Physiology, 299-309. | |
| 25043828 | Lei, Z., et al. 2014. Reduced expression of IA channels is associated with postischemic seizures in hyperglycemic rats.. Journal of Neuroscience Research, 1775-1784. | |
| 21129448 | Bourdeau, M.L., et al. 2011. KChIP1 modulation of Kv4.3-mediated A-type K(+) currents and repetitive firing in hippocampal interneurons.. Neuroscience, 173-187. | |
| 20483361 | Liu, W., et al. 2010. High-mobility group box 1 (HMGB1) downregulates cardiac transient outward potassium current (Ito) through downregulation of Kv4.2 and Kv4.3 channel transcripts and proteins.. Journal of Molecular and Cellular Cardiology, 438-448. | |
| 20154682 | Anderson, D., et al. 2010. Regulation of neuronal activity by Cav3-Kv4 channel signaling complexes.. Nature Neuroscience, 333-337. | |
| 19953263 | Wagner, M., et al. 2010. Larger transient outward K(+) current and shorter action potential duration in Galpha(11) mutant mice.. Pflügers Archiv: European Journal of Physiology, 607-618. | |
| 19768467 | Soltysinska, E., et al. 2009. Transmural expression of ion channels and transporters in human nondiseased and end-stage failing hearts.. Pflügers Archiv: European Journal of Physiology, 11-23. | |