Anti-Kir2.1 K+ Channel Antibody (N112B/14)
Our Anti-Kir2.1 K+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N112B/14. It detects mouse and rat Kir2.1 K+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Adult rat hippocampus immunohistochemistry.
Product Specific References for Applications and Species
- Immunocytochemistry: Mouse
- Immunohistochemistry: Mouse | Non-Human Primate
- Immunoprecipitation: Human | Rat
- PLA: Rat
- Western Blot: Human | Mouse | Rat
- Additional Publications: Unspecified
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 29802197 | 1:50 | Cheng, L., et al. 2018. Coupling of Smoothened to inhibitory G proteins reduces voltage-gated K+ currents in cardiomyocytes and prolongs cardiac action potential duration. . Journal of Biological Chemistry, 11022-11032. |
| 21507952 | 1:10 (supe) | Cheng, L., et al. 2011. Cortactin is required for N-cadherin regulation of Kv1.5 channel function.. The Journal of Biological Chemistry, 20478-20489. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 30551997 | 1:200 | Pignatelli, M., et al. 2019. Engram Cell Excitability State Determines the Efficacy of Memory Retrieval. Neuron, 274-284. |
| Immunohistochemistry: Non-Human Primate | ||
| PMID | Dilution | Publication |
| 33188005 | not listed | McLaughlin, A.J., et al. 2020. Glycinergic Inhibition Targets Specific Off Cone Bipolar Cells in Primate Retina. eNeuro, . |
| Immunoprecipitation: Human | ||
| PMID | Dilution | Publication |
| 29514831 | not listed | Ponce-Balbuena, D., et al. 2018. Cardiac Kir2.1 and NaV1.5 Channels Traffic Together to the Sarcolemma to Control Excitability. Circulation Research, 1501-1516. |
| Immunoprecipitation: Rat | ||
| PMID | Dilution | Publication |
| 29184507 | 2ug | Utrilla, R.G., et al. 2017. Kir2.1-Nav1.5 Channel Complexes Are Differently Regulated than Kir2.1 and Nav1.5 Channels Alone. Frontiers in Physiology, 903. |
| PLA: Rat | ||
| PMID | Dilution | Publication |
| 36060074 | 1:200 | Xu, Y., et al. 2022. Hypoxia Inhibits the Cardiac I Current Through SUMO Targeting Kir2.1 Activation by PIP2. iScience, 104969. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 35762211 | 1:500 | Jimenez-Vazquez, E.N., et al. 2022. SNTA1 Gene Rescues Ion Channel Function and is Antiarrhythmic in Cardiomyocytes Derived from Induced Pluripotent Stem Cells from Muscular Dystrophy Patients. eLife, e76576. |
| 23543060 | not listed | Luo, X., et al. 2013. MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation.. Journal of Clinical Investigation, 1939-1951. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 33237428 | 1:1000 | Hegyi, B., et al. 2020. Hyperglycemia regulates cardiac K+ channels via O-GlcNAc-CaMKII and NOX2-ROS-PKC pathways. Basic Research in Cardiology, 71. |
| 26985008 | 1 : 200 | Lisewski, U., et al. 2016. Increased aldosterone-dependent Kv1.5 recycling predisposes to pacing-induced atrial fibrillation in Kcne3-/- mice.. The FASEB Journal, 2476-2489. |
| 26611208 | not listed | Zhang, X., et al. 2016. Persistent increases in Ca(2+) influx through Cav1.2 shortens action potential and causes Ca(2+) overload-induced afterdepolarizations and arrhythmias.. Basic Research in Cardiology, 45307. |
| 25545278 | not listed | DiFranco, M., et al. 2015. Inward rectifier potassium currents in mammalian skeletal muscle fibres.. The Journal of Physiology, 1213. |
| 24895455 | not listed | Shy, D., et al. 2014. PDZ domain-binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function.. Circulation, 147-160. |
| 22509027 | not listed | Milstein, M.L., et al. 2012. Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia.. PNAS USA, E2134-E2143. |
| 22396414 | 1:100 | Cazorla, M., et al. 2012. Striatal D2 receptors regulate dendritic morphology of medium spiny neurons via Kir2 channels.. Journal of Neuroscience, 2398-2409. |
| 22080862 | not listed | Shen, T., et al. 2011. Tbx20 regulates a genetic program essential to adult mouse cardiomyocyte function.. Journal of Clinical Investigation, 4640-4654. |
| Western Blot: Rat | ||
| PMID | Dilution | Publication |
| 20378750 | 10ug | Farraj, A.K., et al. 2011. ST depression, arrhythmia, vagal dominance, and reduced cardiac micro-RNA in particulate-exposed rats.. American Journal of Repiratory Cell and Molecular Biology, 185-196. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 26205295 | El Gebeily, G., et al. 2015. Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart.. Journal of Molecular and Cellular Cardiology, 85-94. | |