Anti-Kv9.2 K+ Channel Antibody (N460/19)

Name: Anti-Kv9.2 K+ Channel Antibody
Brand: NeuroMab
SKU: 75-459
Price: 319.0 USD
Availability: InStock

Our Anti-Kv9.2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N460/19. It detects mouse and rat Kv9.2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.

Adult rat brain membrane immunoblot

Species Reactivity

Mouse, Rat

Applications

ICC, IHC, WB

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-459

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

Kv9.2

Target Description

Voltage-gated K+ channels are important determinants of neuronal membrane excitability (Pongs, 1999). Moreover, differences in K+ channel expression patterns and densities contribute to the variations in action potential waveforms and repetitive firing patterns evident in different neuronal cell types. Members of the Kv5-Kv11 families code for “silent subunits” that do not express as functional homomultimers. In heterologous expression systems, silent subunits can coassemble with Kv2 and Kv3 subunits and modulate the biophysical characteristics of the latter subunits (Yan L. et al., 2004).

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N460/19

Isotype

IgG1

Applications

ICC, IHC, WB

Host Species

Mouse

Gene Name

Kcns2

Molecular Weight

60-80 kDa

Antigen

Fusion protein amino acids 411-477 (cytoplasmic C-terminus) of mouse Kv9.2 (accession number O35174) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2714205

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

No cross-reactivity reported

Quality Control

Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Kv9.2 (Potassium voltage-gated channel subfamily S member 2) (Delayed-rectifier K(+) channelalpha subunit 2) (Kcns20 (KIAA1144)

UniProt Details

UniProt (Human): Q9ULS6
UniProt (Immunogen Species): O35174

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Anti-Kv9.2 K+ Channel Antibody (N460/19)

SKU: 75-459

Product Details

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