Anti-Navbeta1 Na+ Channel Antibody (N405/74)

Name: Anti-Navbeta1 Na+ Channel Antibody
Brand: NeuroMab
SKU: 75-425
Price: 319.0 USD
Availability: InStock

Our Anti-Navbeta1 Na+ channel mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N405/74. It detects mouse and rat Navbeta1 Na+ channel, and is purified by Protein A chromatography. It is great for use in IHC, ICC.

Species Reactivity

Mouse, Rat

Applications

ICC, IHC

Host Species

Mouse

Available Conjugates

490

550

594

650

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Data Sheet

SKU: 75-425

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

Navbeta1 Na+ channel

Target Description

Werner syndrome ATP-dependent helicase, WRN RecQ Like Helicase or DNA Helicase, RecQ-Like Type 3 is encoded by the gene WRN and is a member of the WRN RecQ Like Helicase family. WRN acts as a DNA helicase that is involved in DNA repair, replication, recombination and maintenance of DNA stability. WRN is a multifunctional enzyme with ATP dependent helicase activity, and is the only RecQ helicase member that has 3’ to 5’ exonuclease activity. WRN is expressed within the central nervous system and brain Diseases associated with this gene include Werner Syndrome and Medulloblastoma.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N405/74

Isotype

IgG2a

Applications

ICC, IHC

Host Species

Mouse

Gene Name

Scn1b

Molecular Weight

24 kDa

Antigen

Fusion protein amino acids 14-160 (extracellular N-terminus) of rat Navbeta1 (accession number Q00954) produced recombinantly in E. Coli

Species Reactivity

Mouse, Rat

Antibody Registry ID

AB_2637012

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Does not cross-react with Navbeta2, Navbeta3 or Navbeta4

Quality Control

Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Sodium channel subunit beta-1

UniProt Details

UniProt (Human): Q07699
UniProt (Immunogen Species): Q00954

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Anti-Navbeta1 Na+ Channel Antibody (N405/74)

SKU: 75-425

Product Details

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