Our Anti-Neuregulin-HBD (Heparin binding domain, Type I/II) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N120A/9. It detects human Neuregulin-HBD (Heparin binding domain, Type I/II), and is purified by Protein A chromatography. It is great for use in ICC.
Transfected cell immunofluorescence: COS cells expressing Flag-tagged human Neureguline-HBD. Red = rabbit anti-Flag, Green = N120A/9.
Neuregulin-HBD (Heparin binding domain, Type I/II)
Neuregulin 1 is encoded by the gene NRG1. NRG1 is a member of the neuregulin family. NRG1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. NRG1 is expressed in the nervous system, intestine, muscle, and heart. Diseases associated with NRG1 include Schizphrenia 6 and Lung Cancer.
Purified by Protein A chromatography
1 mg/mL
Monoclonal
N120A/9
IgG2a
ICC
Mouse
NRG1 GGF HGL HRGA NDF SMDF
None Reported
Fusion protein amino acids 14-117 (extracellular N-terminus) of human Neuregulin-1 (accession number Q02297) produced recombinantly in E. Coli
Human
AB_10672368
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Liquid
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Unconjugated
No cross-reactivity reported
Each new lot of antibody is quality control tested on cells overexpressing target protein and confirmed to give the expected staining pattern.
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
United States
24 months from date of receipt
Shipped on ice packs
Pro-neuregulin-1, membrane-bound isoform (Pro-NRG1) [Cleaved into: Neuregulin-1 (Acetylcholine receptor-inducing activity) (ARIA) (Breast cancer cell differentiation factor p45) (Glial growth factor) (Heregulin) (HRG) (Neu differentiation factor) (Sensory and motor neuron-derived factor)]
