Anti-Neurexin-1-Beta (Staining) Antibody (N170A/1)
Our Anti-Neurexin-1-Beta (staining) mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N170A/1. It detects human and mouse Neurexin-1-Beta (staining), and is purified by Protein A chromatography. It is great for use in ICC, WB.
Transfected cell immunoblot: extracts of COS cells transiently transfected with Flag-tagged Neurexin-1-Alpha, Neurexin-1- Beta or untagged Kv2.1 plasmid and probed with N170A/1 TC supe (left) and rabbit anti-Flag (right).
Product Specific References for Applications and Species
- Flow Cytometry: Mouse | Rat
- Immunocytochemistry: Mouse | Non-Human Primate | Rat
- Immunohistochemistry: Mouse
- Western Blot: Human | Mouse | Non-Human Primate
- Additional Publications: Unspecified
| Flow Cytometry: Mouse | ||
| PMID | Dilution | Publication |
| 33185603 | 2.5 ug/mL | Singh, A., et al. 2020. Functional Integrity of Synapses in the Central Nervous System of Cognitively Intact Individuals with High Alzheimer’s Disease Neuropathology Is Associated with Absence of Synaptic Tau Oligomers. Journal of Alzheimers Disease, . |
| 31685865 | 2.5ug/ml | Forner, S., et al. 2019. Intra- and extracellular β-amyloid overexpression via adeno-associated virus-mediated gene transfer impairs memory and synaptic plasticity in the hippocampus. Scientific Reports, 15936. |
| 27986924 | 2.5ug/ml | Prieto, G.A., et al. 2017. Pharmacological Rescue of Long-Term Potentiation in Alzheimer Diseased Synapses. Journal of Neuroscience, 1197-1212. |
| Flow Cytometry: Rat | ||
| PMID | Dilution | Publication |
| 26305968 | 1:400 | Prieto, G.A., et al. 2015. Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus. PNAS USA, E5078-E5087. |
| Immunocytochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 29619614 | 2.5ug/ml | Prieto, G.A., et al. 2019. TNFα and IL-1β but not IL-18 Suppresses Hippocampal Long-Term Potentiation Directly at the Synapse. Neurochemistry Research, 49-60. |
| Immunocytochemistry: Non-Human Primate | ||
| PMID | Dilution | Publication |
| 37048156 | not listed | Feller, B., et al. 2023. α-Synuclein Preformed Fibrils Bind to β-Neurexins and Impair β-Neurexin-Mediated Presynaptic Organization. Cells, 1083. |
| Immunocytochemistry: Rat | ||
| PMID | Dilution | Publication |
| 29760652 | not listed | Yamagata, M., et al. 2018. Cadherins Interact With Synaptic Organizers to Promote Synaptic Differentiation.. Frontiers in Molecular Neuroscience, 142. |
| 23426688 | 1:1000 | Futai, K., et al. 2013. Specific trans-synaptic interaction with inhibitory interneuronal neurexin underlies differential ability of neuroligins to induce functional inhibitory synapses.. Journal of Neuroscience, 3612-3623. |
| Immunohistochemistry: Mouse | ||
| PMID | Dilution | Publication |
| 22355283 | not listed | Yamagata, M., et al. 2012. Transgenic strategy for identifying synaptic connections in mice by fluorescence complementation (GRASP).. Frontiers in Molecular Neuroscience, 18. |
| Western Blot: Human | ||
| PMID | Dilution | Publication |
| 23536886 | not listed | Zeng, L., et al. 2013. Functional impacts of NRXN1 knockdown on neurodevelopment in stem cell models. PLoS One, e59685. |
| Western Blot: Mouse | ||
| PMID | Dilution | Publication |
| 39013526 | 1:1000 | Currie, J., et al. 2024. Using FASS-LTP in postmortem mice brain tissues to assess pathological synaptic function. Journal of Neuroscience Methods, 110219. |
| 34133920 | 1:500 | Klatt, O., et al. 2021. Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.. Cell Reports, 109266. |
| Western Blot: Non-Human Primate | ||
| PMID | Dilution | Publication |
| 36697254 | not listed | Lee, A.K., et al. 2023. SorCS1 inhibits amyloid-β binding to neurexin and rescues amyloid-β-induced synaptic pathology. Life Science Alliance, e202201681. |
| Additional Publications: Unspecified | ||
| PMID | Publication | |
| 30707832 | Jeon, J., et al. 2019. Robust Induced Presynapse on Artificial Substrates as a Neural Interfacing Method. ACS Applied Materials and Interfaces, 7764-7773. | |
| 25428619 | Fang, M., et al. 2016. Neuroligin-1 Knockdown Suppresses Seizure Activity by Regulating Neuronal Hyperexcitability. Molecular Neurobiology, 270-284. | |