Anti-NKCC1 Antibody (N161/20)

Name: Anti-NKCC1 Antibody
Brand: NeuroMab
SKU: 75-229
Price: 319.0 USD
Availability: InStock

Our Anti-NKCC1 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N161/20. It detects human, mouse, and rat NKCC1, and is purified by Protein A chromatography. It is great for use in DB.

Serial dilutions of BSA-conjugated modified and unmodified peptides dotted onto membrane and probed with N161/20 TC supe (left) and a mouse loading control (right).

Species Reactivity

Human, Mouse, Rat

Host Species

Mouse

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Data Sheet

SKU: 75-229

Volume: 100 µL

Variant

Price:

$319.00

Quantity:

Product Details

Target

NKCC1

Target Description

NKCC1 or Solute carrier family 12 member 2, is encoded by the gene SLC12A2. NKCC1 is a membrane bound protein that is involved in sodium, potassium and chloride transport and reabsorption and is expressed in many tissues.

Format

Purified by Protein A chromatography

Concentration

1 mg/mL

Clonality

Monoclonal

Clone

N161/20

Isotype

IgG1

Host Species

Mouse

Gene Name

SLC12A2 NKCC1

Molecular Weight

131 kDa

Antigen

Synthetic peptide amino acids 208-223 (YYLR[pT]FGHN[pT]MDAVPR) of human NKCC1 (accession number P55011)

Species Reactivity

Human, Mouse, Rat

Antibody Registry ID

AB_2285991

Storage

Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.

Physical State

Liquid

Production Notes

Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.

Buffer

10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125

Conjugate

Unconjugated

Specificity

Cross-reacts with non-phosphorylated protein by ELISA

Usage Statement

These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.

Country of Origin

United States

Expiration

24 months from date of receipt

Shipping

Shipped on ice packs

Synonyms

Solute carrier family 12 member 2 (Basolateral Na-K-Cl symporter) (Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1)

UniProt Details

UniProt (Human): P55011
UniProt (Immunogen Species): P55011

Product Specific References for Applications and Species

Immunohistochemistry: Mouse
Western Blot: Mouse

Immunohistochemistry: Mouse
PMID	Dilution	Publication
26539026	not listed	Frederikse, P.H., et al. 2015. KCC2 expression supersedes NKCC1 in mature fiber cells in mouse and rabbit lenses. . Molecular vision, 1142.

Western Blot: Mouse
PMID	Dilution	Publication
25066727	1:1000	Campbell, S.L., et al. 2015. GABAergic disinhibition and impaired KCC2 cotransporter activity underlie tumor-associated epilepsy.. Glia, 23-36.

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Anti-NKCC1 Antibody (N161/20)

SKU: 75-229

Product Details

Product Specific References for Applications and Species

Bulk Order Anti-NKCC1 Antibody

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